Control of coccidiosis in cultured nutria

Pathogen 1 coccidiosis (C. The pathogen of ccidiosis is sporozoa, which is a parasitic single-celled protozoa. Coccidia parasitize in the mucosal epithelial cells of the small intestine and reproduce asexually (mitotic reproduction) for many generations, resulting in many new individuals. After a number of cleavage reproduction, sexual reproduction (gametogeny) is carried out to form many megaspores (female) and microspores (male). The macrospores enter the intestine and combine here. after fertilization, the megaspore is covered with a bilayer membrane into an oocyst and wanders out of the body with the feces. Oocysts are highly resistant to disinfectants, but die in dry air within a few days. The temperature of 55C was killed in 15 minutes, the water temperature of 80C in 10 seconds, and 100C in 5 seconds. (epidemiology) nutria of all ages are infectious to coccidiosis, but 12-month-old mice are the most susceptible and have the highest mortality. Adult female rats often become the carriers of coccidiosis and are the main source of infection in their offspring.

The disease is often transmitted through contaminated feed, drinking water and enclosures, as well as appliances. Wild rats, house rats and flies can also be vectors. (clinical symptoms) the body temperature of the diseased mice dropped from 37 ~ 38C to 35.5 ~ 36C, with loss of appetite, depression of spirit, diarrhea, blood-like mucus in feces, dull coat, abdominal swelling, gas production in the intestines and inactivity. Due to the participation of mechanical, toxin and bacteria, the diseased rats cause disorders of the nervous system, resulting in a series of disorders, such as liver dysfunction, disturbance of substance metabolism, dyspepsia, cerebral anemia, vascular fragility and increased permeability. The clinical symptoms of mild coccidia infection and most adult mice were not obvious, but the offspring died 15 days after the occurrence of clinical symptoms. (pathological changes) high degree of cadaver failure, anemia, ascites, stomach emptiness. Liver, beer and kidney are congested. There is catarrhal inflammation in the small intestinal mucosa, and the lesions are often covered with erosive areas. Chronic pass-through? There are gray-white nodules in the mucous layer of the small intestine, which are filled with coccidial oocysts. In patients with hepatic coccidiosis, the liver shows symptoms of jaundice.

Factors such as incomplete nutrition in diet, lack of vitamins and inorganic salts, insufficient drinking water, poor sanitation in pools and enclosures, and so on, can aggravate the disease. The discovery of coccidial oocysts in the feces of diseased mice is the main basis for the diagnosis of the disease. A large number of coccidiosis at different developmental stages can be diagnosed according to pathological and anatomical changes such as inflammatory lesions, erosion, ulcers, nodules, and small intestinal mucosal scraping. (prevention and control measures) each young mouse was orally given phthaloylsulfamethazol O.1 g, twice a day, and the adult mouse was treated with O.2 g for 7 days. This medicine can also be dissolved in drinking water to make sick rats drink by themselves, with a dose of 0.4-0.5 grams per day. 0.5 grams of sulfamethoxine per kilogram of body weight per day for 5 days. In order to prevent the disease, 0.1% iodine solution can be used as drinking water. Stop drinking for 5 days after taking it for 10 days, and then take it again. The ideal measures to prevent nutria coccidiosis are to keep the enclosure clean and dry, to change the mat grass at any time, to disinfect the nest regularly with flame torch or hot Lysol solution, and to disinfect food utensils with 23% gram Liao Lin solution. There are a large number of coccidia oocysts in the feces of diseased mice, which must be disposed of properly and can only be used as farm manure after biological fermentation.