4-day-old piglets have neurological symptoms, case sharing + prevention and treatment plan

Case: on May 3, Mr. Li, a farm with 30 sows in Nanyang, Henan Province, sent a video call for treatment. The farm has been self-breeding. Recently, piglets under several sows have vomiting, yellowing dysentery and eyelids swelling for 4 days in a row. Unable to stand up, paddling water movement, more than 20 piglets have died. I hope the author can come to the doctor, after the author arrived at the scene, there are still 17 piglets with symptoms.

Case: on May 3, Mr. Li, a farm with 30 sows in Nanyang, Henan Province, sent a video call for treatment. The farm has been self-breeding. Recently, piglets under several sows have vomiting, yellowing dysentery and eyelids swelling for 4 days in a row. Unable to stand up, paddling water movement, more than 20 piglets have died. I hope the author can come to the doctor, after the author arrived at the scene, there are still 17 piglets with symptoms.

Autopsy changes: there were suppurative ulcer in piglet tonsil, white necrosis in liver, white necrosis in spleen and a small amount of bleeding in kidney.

Case diagnosis: from the analysis of clinical symptoms and changes of plane examination, it was judged as porcine pseudorabies.

Treatment: one nasal drip for sick piglet pseudorabies gene deletion vaccine and one nasal drip for other 2-day-old piglets. Three sick piglets basically died three days after nasal drip, and the other piglets have been cured.

Case study: the pig farm sows have been protected against pseudorabies vaccine twice a year, and the pig farm uses pregnant sows and lactating sows to be raised in a pen, which increases the risk of infection. After the occurrence of the disease in pigs, early diagnosis, early treatment and timely comprehensive prevention and control measures must be taken in order to control the epidemic situation as soon as possible. The immunization plan and procedure of the pig farm are not perfect and need to be improved.

The clinical symptoms of the disease: the stage of the disease is different, and the symptoms are different.

a. Performance of pregnant sows

Pseudorabies occurs mainly in the third trimester of pregnancy in ① pregnant sows, which is characterized by abortion, stillbirth and mummified fetus.

The size of the fetus aborted by ② is consistent.

b. Suckling piglets: starting from the third day after birth, the piglets showed neurological symptoms such as fever, mental depression, vomiting, yellow dysentery, eyelid swelling, ataxia, epileptic convulsions and so on.

c. Nursing pigs and fattening pigs: the main manifestations are sneezing, coughing and panting, runny nose and other respiratory symptoms.

Summary and analysis: pseudorabies has no specific drugs, mainly vaccine immunity. Porcine pseudorabies virus occupies space in the way of occupying space. once wild pseudorabies virus occupies space in the mucosal epithelium of pig nasal cavity and respiratory tract, it is easy to occur when the resistance of pigs is low. at the age of 2-3 days of birth, a pseudorabies vaccine was dripped into the nose of piglets, occupying the respiratory epithelial cells, and the wild virus could not invade the body. A reasonable vaccine immunization procedure was established according to the situation of pig farm, and porcine pseudorabies genetic engineering vaccine was enhanced. (source: Toutiao veterinarian Xu)