Immune Technology of Pigs against Blight

Reference immunization program

1 Vaccines recommended for universal vaccination

1.1 CSFV immunity

Newborn piglets were vaccinated with the first routine dose of attenuated classical swine fever virus vaccine at 20 days of age. (It is best to promote early zero immunization).

Piglets 50 - 60 days old, for routine second immunization.

Reserve pigs were selected and vaccinated three times before mating.

1.2 swine paratyphoid immunity

The whole herd of adult and replacement pigs were immunized with conventional doses in March and September.

Piglets older than 30 days of age are vaccinated head by head with a routine dose.

1.3 Immunization of swine erysipelas and swine pulmonary disease

The whole herd of adult and replacement pigs were immunized with conventional doses in March and September.

Replacement pigs were injected once in June and July of the following year.

60 - 75 days old (or swine fever-erysipelas-pulmonary disease triple vaccine) according to the conventional head dose vaccination.

1.4 Japanese encephalitis

Immunization is carried out 1 - 2 months before mosquitoes appear in epidemic areas every year.

1.5 Blue ear disease, pseudorabies, parvovirus immunity

Using "blue-fine-false triple inactivated vaccine", gilts were immunized intramuscularly 2 - 3 weeks before breeding; piglets were immunized intramuscularly at 3 - 4 weeks of age; second immunization after weaning.

1.6 yellow and white scour of piglets

The "Piglet Escherichia coli STl-LTB-K88 trivalent genetic engineering vaccine" was used, and the first sow was injected intramuscularly at 40 days and 15 days before birth; the multiparous sow was injected intramuscularly at 15 days before birth; and the piglet was injected intramuscularly at 7 days after birth.

1.7 edema disease

Piglets were injected intramuscularly at 14 - 18 days of age with inactivated vaccine of porcine edema disease.

1.8 swine streptococcosis

It is best to use "local strain inactivated vaccine", the epidemic area (field) in 60 days of age for the first time, after the spring and autumn each year for one time.

2 Reference immunization program for sows

2.1 swine fever

The attenuated vaccine of classical swine fever should be immunized once a year and should be inoculated in the empty gestation period.

2.2 swine erysipelas

Attenuated swine erysipelas vaccine once every six months (spring, autumn once each. It is best to avoid pregnancy when vaccinating.)

2.3 swine pasteurellosis

Attenuated vaccine (oral or injection) and each year in March, September immunization once (can also be in the local epidemic season before vaccination).

2.4 Blue ear, pseudorabies, parvovirus

Immunization application "blue-thin-pseudo-triple inactivated vaccine", 3 - 4 weeks before breeding intramuscular immunization.

2.5 Japanese encephalitis

Immunization is carried out 1 - 2 months before mosquitoes appear in epidemic areas every year.

2.6 yellow and white scour of piglets

"Piglet E. coli ST1-LTB-K88 trivalent genetic engineering vaccine" was used intramuscularly at 15 days before birth.

2.7 piglet red diarrhea

Threatened pig farms can use "inactivated vaccine of piglet red diarrhea" or "bivalent genetic engineering vaccine of piglet red diarrhea". One month and half a month before delivery.

2.8 swine streptococcosis

It is best to use "local strain inactivated vaccine", and the epidemic area is immunized twice a year in spring and autumn.

2.9 swine paratyphoid

Immunization (injection or oral) with attenuated swine paratyphoid C500 vaccine was performed once in March and September of each year.

2.10 other vaccines

For example,"asthma vaccine" and "viral diarrhea vaccine" can be immunized according to the vaccine instructions. To avoid immune interference between vaccines, immunizations should be given seven days apart between two different vaccines (unless explicitly stated not to interfere or reinforce each other).

3 Gilt Reference Immunization Program

3.1 Swine fever is vaccinated three times before breeding, and the sows are the same after breeding.

3.2 Blue ear, pseudorabies, parvovirus

Immunization application "blue-thin-pseudo-triple inactivated vaccine", intramuscular immunization 2 - 3 weeks before breeding.

3.3 piglet yellow diarrhea

Using the "piglet E. coli ST1-LTB-K88 trivalent genetic engineering vaccine", the first sow was injected intramuscularly at 40 days and 15 days before birth.

4 Vaccination precautions

4.1 immune interference problem

Other diseases can be carried out according to the instructions for the use of vaccines for each disease: in principle, in order to prevent interference between vaccines, immunization should be carried out at least 5 - 7 days apart between two different vaccines (except for those clearly marked as not interfering with each other or reinforcing each other).

4.2 timing of immunization

It is best to use immune surveillance as a scientific basis for determining the timing of immunization (vigorously promote immune surveillance techniques for major diseases).

4.3 Improve and maintain the "immune quality" problem

Improve and maintain the "uniformity of herd antibodies" and eliminate pigs with low antibody sensitivity.

4.4 Environmental cleanliness issues

Try to reduce the pathogen concentration (pathogen pollution degree) in the external environment and maintain it dynamically for a long time (it can be carried out in conjunction with the monitoring of pathogen pollution degree), and eliminate the misunderstanding of "heavy immunity, light disinfection".

4.5 feed problem

During oral bacterial vaccines, distiller's grains, antibiotics, fermented acid swill and high fever feed shall not be fed.

4.6 Medication during immunization

Within 5 - 7 days before and after immunization, drugs that have a negative impact on the immune response of the vaccine should be avoided (such as chloramphenicol, tetracycline, etc., drugs that can reduce white blood cells or antibacterial drugs that inhibit bacterial vaccines).

4.7 Disinfection during immunization

When using various attenuated live vaccines for immunization (especially when drinking water, mixed feeding, aerosol immunization), it is strictly prohibited to use various disinfectants for disinfection within 7 - 10 days before and after immunization (especially drinking water disinfection and pig spray, fumigation).

4.8 Cross-infection and safe injection

4.8.1 Sterilization of inoculation equipment Inoculation equipment (syringes, needles, etc.) must be sterilized in strict accordance with requirements.

4.8.2 A pig a needle strictly prevent "a needle to the end" injection method. It is best to do "one pig a needle"(every injection of a pig for a needle).

4.8.3 Emergency vaccination sequence Emergency immunization should be carried out in the order of "relative clean group presumed healthy group threatened group and disease group". The sequence of asymptomatic mild symptoms and severe symptoms was followed in the disease cluster.

4.8.4 Safety science injection problem ear and neck intramuscular injection.

4.8.5 Under normal circumstances, immunization of sows during pregnancy should be avoided as much as possible (except emergency immunization).