Treatment of Porcine Toxoplasma gondii

Porcine toxoplasmosis is a zoonotic infectious disease caused by Toxoplasma gondii. It is most common in pigs and can be caused by traumatic contact or eating raw meat infected with the disease. therefore, it is of great significance to ensure the development of aquaculture and human health to do a good job in pre-slaughter quarantine and post-mortem inspection of Toxoplasma gondii in designated slaughterhouses.

1 ante-mortem quarantine

Pigs with swine toxoplasmosis have elevated body temperature up to 41-42 ℃, loss of appetite or loss of appetite, runny nose, cough or dyspnea, anemia, conjunctival congestion, etc., similar to the clinical symptoms of classical swine fever and swine erysipelas, but there are no hemorrhagic spots on the skin.

2 postmortem inspection

The flesh of pigs suffering from acute toxoplasmosis is not bloodletting, the skin of the whole body is mostly purplish red, and there are yellow clear effusion in the skin of two ears, neck, lower abdomen, limbs, buttocks and tail.

2.1 enlargement and induration of lymph nodes, mainly in mesenteric lymph nodes, gastric lymph nodes, liver lymph nodes, lung lymph nodes, slightly swollen to egg size, especially mesenteric lymph nodes. Generally, 3 to 5 or more mesenteric lymph nodes can be seen in the middle and posterior segment of jejunum, with hard and brittle feeling during incision, brick red or grayish red in section, and myeloid swelling of all mesenteric lymph nodes in acute infection. The section is yellowish-white, the periphery is khaki, there is a large amount of serous exudation, and there is edema between the nearby tissues.

2.2 the liver is generally turbid and swollen, with small punctate bleeding or blood stasis, large and brittle hepatomegaly, and yellow-white or gray-white necrotic spots of different sizes.

2.3 incomplete pulmonary withdrawal, often hyperemia, edema, interstitial dilatation, gray color, acute infection, high pulmonary hyperemia, edema, sometimes bleeding, necrosis and compensatory emphysema, a large amount of fluid outflow from the section, and red foam in the trachea.

2.4 spleen acute infection, often enlarged 2 to 3 times, brown fantasy: or cherry red, the surface is often a number of soybean grains of hemispherical protuberance, section blurred, sometimes yellow-white necrotic focus.

2.5 the kidney is generally only red in color, occasionally with turbid swelling and a few bleeding spots or spots, and sometimes near the auricle or coronary sulcus.

3Diagnostic

3.1 the clinical symptoms and postmortem pathological changes of this disease are very similar to those of classical swine fever and swine erysipelas, so the differential diagnosis is mainly based on the pathological changes of the spleen (there are often several large hemispherical protuberances of soybeans on the surface). Combined with other pathological changes to make the diagnosis, do not be confused with swine fever, so as to avoid misdiagnosis, laboratory diagnosis can also be made.

10min was fixed with methanol, 40min was stained with 25-fold diluted Giemsa staining solution, washed with neutral distilled water and examined under 800x microscope. Microscopic examination showed that there were various forms of Toxoplasma gondii, most of which were obtusely round at one end and pointed at the other, a few were blunt at one end and pointed at the other, but in a straight line, some were bow-shaped, or bean-shaped, some were obtusely round and curved at both ends, some were hammer-shaped, some were rod-shaped, and the shapes were different.

4 treatment

4.1 carcasses and internal organs with acute porcine toxoplasmosis were destroyed.

4.2 after the diseased organs and lymph nodes were removed, they were used for industrial use or destruction, and the flesh and other organs were treated with high temperature.