Comprehensive and practical techniques for prevention and control of goose cholera

Goose cholera is becoming more and more serious in China, and many farmers ignore the prevention and control, resulting in serious losses. The disease is an acute septic infectious disease caused by Pasteurella multocida; it often occurs in winter and spring, the incidence of adult geese is more than that of young geese, the untimely mortality rate is more than 80% and 95%, and the destruction loss is not uncommon. The goose house is damp, dark, crowded, abrupt climate, lack of vitamins. Malnutrition, internal and external infection of parasites can induce the disease.

I. prevalence and symptoms

The disease is a common infectious disease of chickens, ducks, geese, birds and birds. Sick poultry, infected birds and polluted environment, utensils, feed, drinking water, ponds and means of transport are all sources of infection of the disease. Goose swimming in polluted water can also cause an outbreak of the disease. In addition, flies, ticks and mites can also spread the disease. The disease is mainly infected by throat, upper respiratory tract mucosa, digestive tract and injured skin. The disease can occur all the year round, but it occurs frequently and seriously from September of that year to March of next year.

The incubation period of natural infection is mostly 3-9 days, and the clinical symptoms are the most acute, acute and chronic. The most acute type: most common in the early stage of the epidemic, with five symptoms, often fall to the ground suddenly or fall suddenly during mating, and die when the wings flutter a few times; sometimes there is no abnormality in feeding at night, but die in the house the next morning; most of the infections in obese and high-yield geese are the most acute. Acute type: the most common; diseased geese are depressed, isolated, crouched on the ground or under their head and wings, do not eat, drive slowly, do not want to enter the water, diarrhea, discharge white or yellowish green thin feces; sometimes there are blood clots or blood lines in the feces; the body temperature is as high as 42-43 ℃, it is difficult to breathe and die in 2-3 days. Chronic type: transformed from acute type; diseased geese continue to have dysentery and emaciation, and in the later stage, many joints are enlarged, suppurated, mentally poor, eat little or only drink water, drive out broken lines; some appear respiratory tract inflammation, serous or viscous secretions flow out of the nasal cavity, dyspnea, anemia, sarcoma pale, the course of disease can reach more than 1 month, and finally have to be eliminated.

The liver shape of the most acute type of dead body had varying degrees of swelling and congestion, a small number of scattered bleeding spots in the corona and epicardium, and no obvious lesions in the digestive tract. Acute goose serosa, mucosal bleeding, pericardial effusion, pericardial hemorrhage, left and right ventricle, coronary sulcus bleeding, hepatomegaly, hyperemia, crisp, millet large brown or gray-white necrotic foci under the liver capsule, tracheobronchial mucosal congestion and bleeding; pulmonary congestion, subcapsular hemorrhage; small intestinal mucosa inflammation. Chronic type of small intestine and ileum have varying degrees of catarrhal inflammatory lesions, intestinal mucosal exfoliation, submucosal edema, intestinal wall collapse, foot joint inflammatory swelling, suppuration.

II. Comprehensive prevention and treatment

1. Prevention: ① always keeps the goose house dry, ventilated and ventilated, and changes to sun-dried bedding every 3-5 days. ② climate abrupt change to do a good job of cold prevention and cooling work. The supply of ③ feed should not change suddenly, and vitamins and minerals should meet the needs of growth and development. ④ drinking fountains, grains, etc. are washed with 2% sodium hydroxide solution every day and then washed with clean water; goose houses, floors and utensils should be cleaned and sterilized with 5% lime water or 1% bleach solution. ⑤ found that diseased geese should be isolated, treated and disinfected in time, and the carcasses of diseased geese should be deeply buried in time and strictly disinfected. ⑥ diluted 1010 attenuated fowl cholera vaccine with water according to the instructions for use, then provided more points for geese to drink or mixed the drinking water with an appropriate amount of cornmeal to make gruel, so that the geese could finish eating within 2 hours, and the immunity period could reach 8 months. ⑦ VC attenuated avian cholera vaccine was diluted 100 times with aluminum glue, and 0.5 × 1 ml was injected subcutaneously into the neck of each goose. It was repeated after two weeks, and the immunization period was up to 3 months. ③ emergency prevention and treatment with anti-fowl cholera high immune serum subcutaneous injection of 3ml, repeated every other day, has the effect of prevention and early treatment.

2, treatment: ① 10% sulfadiazine intramuscular injection, 0.5ml / kg injection, twice a day, continuous treatment for 2 days, the curative effect is more than 95%. ② sulfamethazine powder was fed with 0.5%-1% mixed feed for 5 days, and the effect was remarkable. ③ dimethoprim was fed with 0.3% 0.5% dimethoprim for 5 days. ④ penicillin was injected intramuscularly 2-3 times a day for 3-4 days, and the curative effect was more than 85%. ⑤ streptomycin 10 ~ 200000 units was injected intramuscularly 2-3 times a day for 3-4 days. ⑥ oxytetracycline powder was fed with 0.05% oxytetracycline powder mixed with 0.1% oxytetracycline powder, or 0.15 ±0.3 grams per goose per day for 2 days, or 25 mg of oxytetracycline per kilogram twice a day for 2 days, with a curative effect of more than 96%. ⑦ wild chrysanthemum 60g, gypsum 15g, boil 250ml of water, after cooling, each goose is given 2 tablespoons at a time, 3 times a day for 2 days, the curative effect can reach more than 90%. If 50% of the water is often drunk by geese, the disease can be prevented. ⑧ seed powder was infused with warm water, 2 grams per feather, 3 times a day, for 2 to 3 days. It can also be fed with 2 grams of mixed feed per feather for 3 days. ⑨ Huoxiang 30g, Rhubarb 30g, Rhubarb 30g, Rhizoma Atractylodes 50g, Scutellaria baicalensis Georgi 30g, Wumei 60g, Magnolia 60g, Huangmei 30g, Radix Isatidis 80g. Except for rhubarb and Wumei, the rest of the medicine was studied and then mixed with feed, 2 grams per feather, twice a day for 2 to 3 days, and the curative effect was more than 95%. If you use rhubarb at the beginning of the disease, you don't need Wumei. If you find that diarrhea has passed 3 days, use Wumei instead of rhubarb. After ⑩ garlic, big green leaf and motherwort were fried in water, the garlic was mashed into mud and fed together with drug dregs, one dose a day, one dose in the morning and evening for 3 ~ 5 days, and the curative effect was more than 96%. ⑾ andrographis paniculata dry product 90%, chicken gold (dry) 8%, licorice (dry) 2%, a total of drying crushed into the end, goose each feather 1g 2g, adult goose 2g irrigated or mixed feed, twice a day for 2 days.