Harm and Countermeasures of Asthma in Pigs

Porcine asthma is a serious infectious disease of pigs with high morbidity and low mortality, resulting in higher costs and lower profits. In China, the loss of pigs infected with the disease is 11.9 yuan more than that of uninfected pigs with the same weight of 100 kg. Infection with Mycoplasma suis alone rarely causes death in pigs, but when infected with other bacteria, it will cause a long course of disease, difficult treatment, a decline in production level, and may lead to a certain mortality. Mycoplasma hyopneumoniae is present in 80% of pig lungs, and more than 90% of pigs eventually develop asthma. Sick pigs and pigs carrying Mycoplasma hyopneumoniae are the source of infection of the disease, and pigs of all breeds and ages can be infected. Through the formation of air, contact (such as breastfeeding), the disease is prevalent.

Environmental factors also play an important role in sucking tract infection in pigs. Poor ventilation often leads to poor air quality and the accumulation of toxic and harmful gases, which increases the susceptibility of pigs to infectious diseases and increases the severity of infection. High concentration of ammonia and overcrowding in pigs can cause stress response in pigs and make pigs more sensitive to infectious diseases. In addition, all kinds of stress can lead to the decrease of pig resistance and create conditions for the outbreak and epidemic of porcine asthma. Poor hygiene and incomplete disinfection will lead to continuous occurrence of pig wheezing disease in our field.

Clinical symptoms of porcine asthma: most of the diseased pigs are characterized by non-sputum dry cough, wheezing, growth stagnation, low mortality and high morbidity, as well as dyspnea, fever and decreased overall production performance. Infected pigs usually have little change in appetite, but can not achieve the normal weight gain rate. When the secondary infection of other bacteria, there will be loss of appetite and dysplasia, there is a high fever or mucinous wet sputum, and lead to an increase in mortality.

In order to prevent and cure porcine asthma, comprehensive measures must be taken:

I. Environmental control and management

1 establish a strict and effective sanitary management and disinfection system, choose an efficient and non-toxic disinfectant to disinfect the enclosure and its surroundings, and disinfect pigs regularly (twice a week before 30kg, once a week for 30kg, once a week for 30kg, once a month for more than 60kg).

(2) to implement the feeding mode of full-in and all-out system, and try to achieve self-reproduction and self-support as far as possible.

(3) pay attention to air quality and strengthen ventilation to ensure a good living environment for pigs.

(4) to ensure the reasonable feeding density of pigs.

(5) to minimize the effects of all kinds of stress on pigs.

6 when introducing breeding pigs, they should be strictly isolated and inspected for 3 months, and should not be introduced until it is confirmed that there is no disease.

II. Drug prevention and treatment

The most sensitive drugs were tylosin and lincomycin. Oxytetracycline and canamycin also have certain effects.

(2) in the prevention and treatment of drugs, pulse administration was adopted, that is, a high concentration of drugs was given at one time to maintain a higher drug concentration in the respiratory tract and lungs, and the effective concentration was maintained for a long time.

(3) dose of commonly used drugs:

Tylosin: (1) 1000ppm was fed continuously for 3 weeks, and (2) 10 mg / kg body weight was injected intramuscularly for three days.

Lincoln mycin: 200ppm in feed was fed continuously for 3 weeks.

(4) although the treatment with antibiotics can relieve the symptoms, it can not eradicate the disease and may still occur after drug withdrawal. Because it can not restore the damaged ciliary structure and function, so the focus should be placed on prevention, especially to take comprehensive preventive measures.

III. Vaccination

1 all pigs, including breeding boars, sows and newborn piglets, should be vaccinated.

(2) Transport, storage and use of the vaccine in strict accordance with the instructions for the use of the vaccine.

(3) the use of antibiotics is prohibited one week before and after immunization.

(4) the use of 3mer is prohibited for 4 weeks before slaughtering.