Prevention and treatment of Porcine circovirus Type 2 infection

So far, there are no effective measures to control and eliminate other diseases caused by porcine circovirus type 2 infection, and there are no effective commercial vaccines and drugs to prevent porcine circovirus type 2 infection. Moreover, porcine circovirus type 2 infection is very resistant to conventional disinfectants, which brings difficulties to the purification of pig farms. At present, comprehensive control measures should be taken.

1. Change and improve the feeding mode to achieve full entry and exit at all stages of production, and avoid mixed feeding of pigs of different ages, so as to reduce and reduce the chance of exposure to porcine circovirus type 2 infection among pigs.

two。 Establish a perfect biosafety system for pig farms, and put disinfection and hygiene through all aspects of pig production. Minimize the pollution of pathogenic microorganisms in pig farms and reduce or eliminate the probability of secondary infection in pigs. Because porcine circovirus type 2 infection is resistant to general disinfectants, broad-spectrum disinfectants should be considered in the selection of disinfectants.

3. Strengthen the feeding and management of pig herds and reduce the stress factors of pig herds. Many stress factors can induce and promote the occurrence of porcine circovirus type 2 infection and aggravate the disease of pigs, resulting in an increase in mortality. therefore, the stress factors of pigs should be reduced as much as possible. avoid feeding mildew deterioration or feed containing mycotoxins, do a good job of ventilation in pig houses, improve the air quality of pig houses, and reduce the concentration of ammonia. Keep the pig house dry and reduce the feeding density of the pig herd.

4. Improve the nutrition level of pigs. As porcine circovirus type 2 infection can lead to the decline of immune function in pigs, nutrition is an important factor affecting porcine circovirus type 2 infection. The incidence and loss of porcine circovirus type 2 infection can be reduced to a certain extent by improving the levels of protein, amino acids, vitamins and trace elements, improving feed quality, increasing feed intake of weaned pigs, feeding wet feed or porridge to piglets and ensuring adequate drinking water for piglets.

5. A perfect drug prevention program was adopted to control the secondary bacterial infection in pigs. There is no effective drug for the treatment of porcine circovirus type 2 infection, even if some secondary bacterial diseases, the treatment effect is not good, therefore, drug prophylaxis should be used in advance to control secondary bacterial infection. In view of the characteristics of porcine circovirus type 2 infection in pigs in China and its application effect in practical production, the following drugs are suggested for prevention.

Administration of ① piglets: long-acting oxytetracycline (200mg / ml) was injected into suckling piglets at 3,7,21 days of age, 0.5ml at a time, or 0.2ml of cephalothiofur (500mg / ml) at 1, 7 days and weaning. One week before weaning to one month after weaning, feed with Tyamicin (50 g / t) + chlortetracycline or oxytetracycline or doxycycline (150 g / t) + amoxicillin (500 g), or add 2% florfenicol (1000-1500 g / t) + tylosin (200-250 g / t). In pig farms with severe secondary infection, 0.2 ml of cephalothiofur (500 mg / ml) can be injected at 28, 35 and 42 days of age.

Medication for ② sows: one week before parturition and one week after parturition, the sows were fed with Zhiyuanjing (100g / ton) + chlortetracycline or oxytetracycline (300g / ton).

6. Do a good job in immunization against swine fever, pseudorabies, porcine parvovirus infection, asthma and other vaccines in pig farms. The use of inactivated porcine asthma vaccine should be advocated in large-scale pig farms, which is beneficial to improve the immunity of respiratory tract and lung of pigs and reduce the secondary infection of respiratory pathogens.