Beware of Acute Dehydration Death Caused by Weather Change in Rabbits

In August 2007, an acute intestinal infectious disease characterized by severe dysentery, dehydration and rapid death occurred in a breeding group of rabbits in a Rex rabbit farm. The incidence is about 60%, and the case fatality rate is 40%. According to epidemiological, clinical symptoms and pathological changes, combined with laboratory tests, it is finally diagnosed as Rex rabbit Taize's disease. The relevant situation is now reported as follows.

I. the course of the disease

A certain farm raised 1000 Rex rabbits, including more than two hundred breeder rabbits. At the beginning of August, when it rained continuously for 5 days and the temperature exceeded 30 degrees for a week, some rabbits in the rabbit group showed diarrhea symptoms. At that time, dissecting diseased rabbits, suspected to be Clostridium welchii, mixed with cyclopropoxide, the effect was not obvious, and the disease developed rapidly, and began to die 2 days later. After laboratory tests, it was diagnosed as Taize's disease infection. Large groups of rabbits were quickly mixed with oxytetracycline, isolated and treated with butylamine and penicillin intramuscular injection.

Second, clinical symptoms

The disease is mainly severe diarrhea, mostly brown paste to water-like. There are often faeces on the hind legs. Diseased rabbits are depressed, do not eat and are rapidly dehydrated, and often die within 12-48 hours after the onset of symptoms. A small number of sick rabbits who have tolerated the acute phase show loss of appetite and emaciation.

III. Pathological changes

The sick and dead rabbits were dehydrated and emaciated, and their hindlimbs contaminated their feces. Diffuse congestion and bleeding appeared in the serosa and mucosa of the ileum, cecum and colon, severe edema and thickening of the intestinal wall, and gas and brown paste content in the cecum and colon. Mesenteric lymph node edema. Severe atrophy of the spleen. The liver is enlarged with many gray-white stripes of necrosis. In a few dead rabbits, there were gray-white striped spots or patchy necrotic areas on the myocardium. The intestinal wall thickened and the intestinal cavity narrowed due to severe necrosis and fibrosis in some diseased rabbits who had tolerated the acute stage.

IV. Diagnosis

According to the clinical symptoms and changes of autopsy, a preliminary diagnosis was made. The mucosal smears of liver necrotic area and intestinal lesion of dead rabbits were examined by Giemsa staining or silver plating staining to prove the presence of Bacillus hairy in the cytoplasm.

V. Prevention and control measures

Timely isolation of diseased rabbits, strengthen disinfection, strengthen feeding management, reduce stress. The unaffected rabbits were mixed with oxytetracycline for five days, and electrolytic multidimensional or glucose water was used to increase the resistance of the rabbits. 60,000 rabbits were injected intramuscularly with butylamine once a day for three days, and the disease was quickly controlled. if the disease is urgent, he will die before he has time for treatment. Two weeks later, there were no new cases, and the large groups were basically under control.

VI. Summary

The disease is mainly infected through the digestive tract. The feces of diseased rabbits, contaminated feed, drinking water and bedding grass are the main sources of infection, and healthy rabbits can be infected after contact. The bacteria invaded the mucosal epithelium of the small intestine, cecum and colon and proliferated slowly at the beginning, with little tissue damage and mostly recessive infection. Once there are a variety of stress factors that lead to the decline of body resistance, bacteria will take advantage of the opportunity to reproduce rapidly, causing intestinal mucosal deep tissue necrosis, systemic infection and serious damage to tissues and organs.

According to investigation and analysis, this disease is likely to have been infected with the disease in a recessive state. The outbreak of the disease was induced by stress factors such as sudden change of climate and mildew of feed.

Through the treatment of this disease, it is found that the effect of butylamine combined with oxytetracycline and electrolysis is obvious for reference.