MySheen

Diagnosis and treatment of canine toxoplasmosis

Published: 2024-11-24 Author: mysheen
Last Updated: 2024/11/24, The disease is a worldwide zoonotic protozoonosis, which exists widely in domestic animals and wild animals. The disease has been reported all over the country. [diagnostic points] (1) Clinical symptoms: most of them are asymptomatic recessive infection. Infection is more common in young dogs and young dogs, and the symptoms are more serious. There are also fatal cases in adult dogs. The symptoms are similar to canine distemper and canine infectious hepatitis. The main symptoms are fever, cough, anorexia, mental malaise, weakness, eye and nose secretions, pale mucous membrane, dyspnea, and even severe.

The disease is a worldwide zoonotic protozoonosis, which exists widely in domestic animals and wild animals. The disease has been reported all over the country.

[main points of diagnosis]

(1) Clinical symptoms: most of them are asymptomatic recessive infection. Infection is more common in young dogs and young dogs, and the symptoms are more serious. There are also fatal cases in adult dogs. Symptoms similar to canine distemper, canine infectious hepatitis, mainly manifested as fever, cough, anorexia, mental malaise, weakness, eye and nose secretions, pale mucous membrane, dyspnea, and even severe hemorrhagic diarrhea. A small number of sick dogs developed severe vomiting, followed by paralysis and other neurological symptoms. Pregnant bitches can have miscarriage or premature delivery, and their puppies often have symptoms such as loose bowels, dyspnea and dyskinesia. Blood examination: in the acute stage, red and white blood cells decreased, neutrophils increased, neutropenia and monocytosis were rare; the total number of leukocytes in chronic cases increased, mainly neutrophils and thrombocytopenia, but there was no tendency to bleed.

(2) Laboratory examination: relying solely on clinical symptoms, it is easy to be confused with canine distemper, especially nervous canine distemper. Therefore, after the comprehensive determination of epidemiological analysis and clinical symptoms, the diagnosis can only be confirmed by detecting pathogens or confirming the increase of antibody titer in serum.

[treatment]

For patients with acute infection, sulfadiazine (SD) can be used, 70 mg per kg body weight, or trimethoprim (TMP), 14 mg per kg body weight, twice a day for 4 days. Due to the low solubility of sulfadiazine, it is easy to precipitate and crystallize in the urine, so it should be taken orally with the same amount of sodium bicarbonate and increase drinking water. In addition, sulfonamide-6-methoxine (sulfamethoxine, sulfonate, SMM, DS-36) or sulfonyl dapsone (SDDS) can be used.

[prevention]

Do not feed raw meat, and prevent dogs from preying on rodents, and prevent cat dung from polluting feed and drinking water.

 
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