Prevention and treatment of Clostridium diarrhea in rabbits
The disease is an acute intestinal infectious disease caused by Clostridium perfringens type An in rabbits, which is characterized by severe diarrhea, foul smell of feces and rapid death.
Etiology
The pathogen is Clostridium perfringens type A.
Epidemiology
Except for lactating rabbits, rabbits of different ages, breeds and genders are susceptible to this pathogen. The incidence of rabbits from 1 month to 3 months old was the highest. The main causes of infection are improper feeding and management, shortage of green fodder, low content of crude fiber, feeding high protein feed or long-distance transportation, sudden climate change and so on. The disease can occur all the year round and occurs frequently in winter and spring.
Clinical symptoms
The incubation period is 2 ~ 3 days, and the long one can be up to 10 days. The clinical features are acute dysentery and watery diarrhea before death. There is no obvious change in spirit and appetite before the emergence of watery diarrhea; after the emergence of watery diarrhea, the spirit is depressed and does not eat. The feces are watery and have a special fishy smell, contaminating the buttocks and hind legs.
Pathological changes
The appearance of the body is not obvious. The stomach is full of chyme, the mucous membrane at the bottom of the stomach is exfoliated, and there are ulcers of different sizes. The small intestine is filled with gas, and the intestinal wall becomes thin and transparent. The cecum and colon are filled with gas and dark green thin content, which can smell decay; the liver becomes brittle and the spleen is dark brown.
Diagnosis.
According to the clinical symptoms and pathological changes, a preliminary diagnosis can be made, and the diagnosis needs further laboratory diagnosis.
Laboratory diagnosis
Pathogen examination: smear microscopic examination (smear of jejunum content, examination of bacteria), isolation and culture (anaerobic meat liver soup and lamb blood Agar plate), toxin isolation and identification (animal test and neutralization test with standard Clostridium perfringens typing serum).
Serological examination: agglutination test, neutralization test and SPA- enzyme-linked immunosorbent assay.
Differential diagnosis
The disease should be distinguished from coccidiosis, rabbit pasteurellosis and salmonellosis.
Prevention and cure
Strengthen feeding management, reduce concentrate feed and increase crude fiber. Vaccine prevention should be used in frequently occurring areas.
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