Diagnosis and treatment of sheep aphthous ulcer

1. Etiology: sheep mouth sores, also known as "sheep infectious pustules", is an infectious disease caused by viruses in sheep and goats. The incidence of oral ulcer in sheep is more than that in 3-6-month-old sheep in spring and autumn, and adult sheep can also be infected, but the incidence is less and shows sporadic epidemic. Sick sheep and infected sheep are the main sources of infection. Natural infection is mainly caused by the introduction of infected sheep from the purchase of sick sheep, or the use of contaminated barns and grasslands.

2. Symptoms: mouth and lip infection was the main symptom of diseased sheep. First of all, scattered small red spots occur on the corner of the mouth, upper lip or nasal mirror, and then gradually become papules and nodules, and then form vesicles or pustules, which spread to the whole lip and the face, eyelids and auricles, forming a large area of filthy scab with cracking and bleeding, granulation tissue proliferation under the scab, and a mulberry-like protuberance of the lips. Oral mucosa is also often damaged, mucosal flushing, blisters occur on the inner face of the lips, gums, cheeks, tongue and soft palate mucosa, followed by pustules and rotten spots. If accompanied by secondary contamination such as necrotic bacilli, it will worsen into a large area of ulcers, deep tissue necrosis, oral stench. Sick sheep are reluctant to eat because of pain, showing salivation, lethargy, loss of appetite or loss of appetite, reduced ruminant, rough coat, and wasting away. Breast-feeding ewes may also suffer from breast disease, mainly due to infection caused by lamb bites.

3, prevention: (1) the disease is mainly transmitted through the injured skin and mucous membrane, so it is necessary to protect the skin and mucous membrane from damage. Try not to feed dry and hard forage and pick out the thorns. Feed the sheep with the right amount of salt to reduce the sheep gnawing on the wall and protect the skin and mucous membrane. (2) do not introduce sheep and their products from the epidemic area, isolate and observe the imported sheep for more than half a month, and then raise them in mixed herds after confirming that they are disease-free. (3) in the endemic areas of the disease, attenuated sheep aphtha vaccine was used for immunization. At the time of vaccination, shake well in the dark according to each dose of vaccine plus normal saline, and each sheep is injected 0.2 ml into the oral mucosa, whichever is a transparent and shiny blister at the injection site. The scab of the mouth and lip of the diseased sheep can also be removed, ground into powder, diluted with 5% glycerol normal saline into 1% solution, and the uninfected sheep can be inoculated with skin scratches, which can produce immunity after about 10 days, and has a good effect on the prevention of the disease.

4. Treatment: (1) first of all, isolate sick sheep and thoroughly disinfect the enclosure and sports ground. (2) give diseased sheep soft, digestible and palatable feed to ensure adequate clean drinking water. (3) first remove the scab from the mouth and lips of the diseased sheep, wash the wound fully with light salt water or 0.1% potassium permanganate water, and then smear the wound with purple potion or iodoglycerin (fully mix iodine tincture and glycerin at 1:1), once or twice a day until healed. (4) Drug treatment: ① was treated with Vuling 0.1g / kg, penicillin potassium or sodium salt 4-5mg / kg, once a day, for 3 days as a course, the interval 2-3 days for the second course, usually 2-3 courses; ② vitamin c 0.5ml, vitamin b 120.02ml, mixed intramuscular injection, twice a day, 3-4 days as a course of treatment.