MySheen

How to do well the immunity of reserve pigs

Published: 2024-11-22 Author: mysheen
Last Updated: 2024/11/22, 1. The production and importance of good immunity of reserve pigs after the first injection of vaccine to pigs, the corresponding antibodies will be produced after a certain period of time, at this time, the antibody titer is low, the maintenance time is short, and they do not have the ability to resist pathogen invasion. but it laid the foundation for the establishment of effective immunity in the future, so it is called basic immunity. Re-inoculation of the same vaccine in a certain period of time can induce the recall response of memory cells after the first vaccination, which can quickly produce high titer and maintenance time in a short period of time.

1. Generation and importance of good immunity in Reserve Pigs

After the first injection of the vaccine to the pig, the corresponding antibody will be produced after a certain period of time, at this time, the antibody titer is low, the maintenance time is short, and it does not have the ability to resist the invasion of pathogens, but it lays the foundation for the establishment of effective immunity in the future. so this immunity is called basic immunity. Reinoculating the same vaccine within a certain period of time can induce the recall response of memory cells after the first vaccination, which can quickly produce antibodies with high titer and lasting for a long time in a short period of time. Only at this time can we achieve the ability to resist the corresponding pathogens, which is called enhanced immunity. However, after a period of time, the titer of the antibody will gradually decrease until it disappears, so it is necessary to strengthen immunization for the second, third and multiple times, each of which can stimulate memory cells to make the antibody rise rapidly. keep the antibody titer at an appropriate level. The success of enhanced immunization is based on basic immunization, so it is impossible to strengthen immunity without basic immunization.

The immunization of backup pigs has a special status as a link between the past and the future. Pig farms need to supplement up to 40% of reserve pigs every year. First-born sows who enter the breeding period have the highest proportion of mummified fetuses and stillbirths, and piglets have the highest incidence of acute death and disease, all of which are closely related to the immune status of backup pigs. so the immunity of backup pigs is the top priority of pig immunity.

two。 Major diseases and procedures that reserve pigs should be immunized

The immunization of reserve pigs should focus on the prevention of severe infectious diseases and reproductive disorders on the basis of protecting pigs.

2.l. Classical swine fever vaccine was vaccinated once at the age of 4 months and 25 days before mating on the basis of immunization at the age of 25-35 days and 60-70 days. 5 portions of classical swine fever cell vaccine or 1-2 portions of classical swine fever tissue vaccine were used each time. Do not use the triple vaccine of classical swine fever, swine erysipelas and swine lung disease, so as to avoid the consequences of the failure of classical swine fever immunity.

2.2. On the basis of immunization of piglets aged 40-45 days, pig foot-and-mouth disease was inoculated once at 100 days old and 25 days before mating. Foot-and-mouth disease type O and Asian type I bivalent inactivated concentrated vaccines should be used according to the instructions.

2.3. On the basis of once vaccination of porcine pseudorabies at weaning, inactivated vaccine should be used at the age of 70 days and 20 days before mating. A live vaccine with gene deletion can only be used in the positive field.

2.4. Porcine parvovirus disease was inoculated with inactivated vaccine 50 days and 30 days before mating.

2.5. Swine Japanese encephalitis is in April, and the reserve sows are vaccinated once 30 days before mating, either attenuated vaccine or inactivated vaccine.

2.6. Porcine blue ear disease was inoculated with inactivated vaccine at the age of 5 months and once again 14 days later. Live vaccines are not available because of the risk of introducing new strains.

2.7. Streptococcus suis was inoculated to pigs weighing more than 20 kg in common areas or in summer and autumn, and then inoculated again two weeks later. Serotype c or Ⅱ vaccine should be selected according to the local epidemic situation, or bivalent vaccine can also be used. Vaccination is not allowed in general areas.

2.8. The inactivated vaccine of porcine asthma was injected intramuscularly at the age of 5-7 days. The inoculation was strengthened again after 2 weeks, and again 1-2 months before mating.

2.9. Transmissible gastroenteritis and epidemic diarrhea in pigs in severe areas, in order to provide high titers of maternal antibodies to newborn piglets to effectively protect their piglets, "infectious substances" can be fed to reserve sows at the age of 5-7 months. For example, the small intestine, intestinal contents and feces of ground pigs were fed for 1-2 days, once every two weeks, for 3 times in total. The protective antibody obtained from "infectious substance" has strong pertinence, high titer, long duration and good immune protection. The use of "infectious substance" should be limited to a certain range, and disinfection should be done afterwards to prevent the expansion of infection.

3. Matters needing attention

3.l. The latter pigs include backup boars and reserve sows, do not miss boars.

3.2. There are many kinds and brands of vaccines to prevent the same disease, so you should read their instructions carefully before use, and be sure to conduct technical consultation when in doubt.

3.3. The recommended immunization time can be advanced or delayed within 7 days. Two kinds of inactivated vaccine or one kind of inactivated vaccine and the other attenuated vaccine can be inoculated on the same day, and two attenuated vaccines should be avoided on the same day.

3.4. The use of sensitive antibiotics should be avoided within 7 days before and after vaccination with attenuated bacterial vaccines such as Streptococcus suis and asthma.

3.5. The immune status of pigs during the nursing period should be investigated clearly. in order to properly adjust the immune procedure of backup pigs.

3.6. After purchasing, each pig should know its real immune type and time as far as possible, in order to supplement the necessary vaccination. In addition, several healthy old sows were mixed in the nursery and sports ground for a period of time to make the purchased pigs infected and adapt to the microbiota of the field and produce corresponding immunity.

3.7. There are many factors causing the low titer of immune antibody, and it is not easy to find, so the immune antibody level of major diseases should be detected at the age of 6-7 months, and remedial measures should be taken in time if the antibody titer is insufficient.

 
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