Characteristics and Control of sudden attack Disease in Sheep

Sheep sudden shock is a kind of toxemia caused by type C Weissoin, which is characterized by acute death, peritonitis and ulcerative enteritis.

I. pathogen

Clostridium welchii, also known as Clostridium perfringens, belongs to the genus Clostridium. The bacteria are gram-positive and can form a capsule in animals, and the spores are located in the center of the cell. Clostridium welchii can be divided into five toxin types according to toxin-antitoxin neutralization test. Sheep sudden shock was caused by Clostridium welchii type C.

II. Popular characteristics

The disease occurs in adult sheep, especially in sheep aged 1-2 years old. it is often prevalent in low-lying, humid areas and winter and spring, mainly through the digestive tract. It is endemic.

III. Clinical symptoms

Type C Clostridium welchii enters the digestive tract of sheep with contaminated feed or drinking water and propagates in the small intestine, especially in the duodenum and jejunum, which mainly produces β toxin and causes the disease of sheep. The course of the disease is short, and most of them die suddenly without seeing the symptoms. Sometimes sick sheep are found to fall out of the herd, lie on the ground, show restlessness, weakness or spasm, and die within hours.

IV. Pathological changes

Autopsy showed that the mucosa of duodenum and jejunum was seriously congested and eroded, and ulcers of different sizes could be seen in some segments. There are many effusions in the body cavity, and it is easy to form cellulose flocs when exposed to air. There's a little bleeding on the serosa. Eight hours after death, blood-like fluid accumulated between the iliac muscles of bone, muscle bleeding, and gas cracks, which was very similar to the pathological changes of black leg disease.

5. Experimental diagnosis

The exudate of collective cavity, spleen side and other diseased materials were collected for bacteriological examination, and the contents of small intestine were tested for toxin to determine the bacterial type.

VI. Differentiation of symptoms

This disease should be distinguished from other diseases of sheep fast epidemic, anthrax, pasteurellosis and other similar diseases. It is mainly distinguished by etiological examination and toxin test.

VII. Prevention and control measures

The main results are as follows: (1) in the frequently affected areas, the sheep were regularly inoculated with "sheep fast epidemic, enterotoxemia, shock triple vaccine" or "sheep fast epidemic, enterotoxemia, sudden shock, lamb dysentery, black plague vaccine" every year, regardless of their size. 5 ml was injected subcutaneously or intramuscularly, and immunity was produced 2 weeks after vaccine injection, and the protective period was up to half a year.

(2) strengthen the feeding and management to prevent the attack of severe cold. Don't go grazing early in the morning when there is frost, and avoid eating frost forage.

(3) the disease can be reduced or stopped by isolating the diseased sheep at the elbow and transferring the sheep to the high dry pasture or grassland.

(4) the course of the disease is short, and it is often too late for treatment. If the course of the disease is slightly delayed, penicillin can be injected intramuscularly, 800000 ~ 1 million units per time, twice a day for 2 ~ 3 days; take sulfadiazine, 5.6g, 3 times for 4 times; or take 10% 20% lime milk 500ml for 2 times. If necessary, 10% sodium coffee 10 ml can be added to 500 '1000 ml 5% 10% glucose solution, intravenous drip.