Treatment of aflatoxin poisoning in pigs

Aflatoxin poisoning in pigs is caused by the intake of feed contaminated by aflatoxin and is characterized by liver damage.

Etiology aflatoxin is a toxin produced by Aspergillus flavus, which is not easy to be destroyed in the external environment, and general heating and boiling can not decompose the toxin (b1 toxin is decomposed only when heating 268 ℃-269 ℃). It is a hepatoma substance. Aspergillus flavus is widely distributed in nature and is easy to propagate and propagate in corn, peanut, rice, wheat seed, cottonseed cake, bean cake, wheat bran and rice bran. And produce toxins, which make the general grain and its by-products mildew and deteriorate. At present, people in many parts of our country are used to feeding pigs with moldy and spoiled food or food that cannot be eaten by humans. Pigs will be poisoned if they eat these moldy and deteriorated feed. Because pig feed contains different grains and rich nutrients, improper storage will also be contaminated by Aspergillus flavus. Aspergillus flavus is the most suitable to reproduce at a temperature of 24 ℃-30 ℃. In grains and grain and oil processing by-products, if the moisture content reaches 20%, 30%, the reproduction is the fastest. Aspergillus flavus is one of the main molds in corn when the most suitable relative temperature for reproduction is 30 ℃. Aspergillus flavus is the main mold when corn is stored at room temperature when the water content of corn is 16.2%-24.4%.

Patients with acute clinical symptoms may die suddenly during exercise or within two days after the onset of the disease. The sick pig is mentally stunted, has no appetite, is weak, stumbles, the mucous membrane is pale, the body temperature is normal, the feces are dry, rectal bleeding, some stand a couple or head against the wall, stand still. Chronic cases, mental depression, stiff walking, eating rubble and soil; being alone, drooping head and arched back, abdominal contraction, dry feces. Some sick pigs show excitement and jump at random. The mucous membrane is yellow-stained, the body temperature is normal, and the skin around the eyes and nose of a few diseased pigs turns red and turns blue gradually.

Pathological changes of acute cases, anemia and bleeding, thoracic and abdominal hemorrhage, serosa surface often have blood stasis spots. Subcutaneous muscle bleeding in front of the thigh and under the scapula. Hepatomegaly, bleeding spots. There are needle-like or ecchymosis bleeding near the serosa of the liver, epicardium and endocardium are common and obvious bleeding, and there is often bleeding in the muscles of the whole body. Chronic cases, hepatobiliary hyperplasia and sclerosis, liver yellow steatosis, white spots or necrotic lesions on the liver surface, pleural and peritoneal effusion. The renal cavity is pale and swollen. Systemic lymph node hyperemia and edema.

Prevention insisting on not feeding moldy feed is the fundamental measure of prevention. To prevent feed mildew is also an important part of prevention.

1. Grain should be harvested in time after maturity, thoroughly dried, ventilated and stored to avoid mildew.

two。 Strengthen the preservation of feed, pay attention to keep dry, especially in warm and rainy areas or seasons, but also to prevent feed mildew.

3. Do not feed moldy grains or food to pigs.

4. Once pig poisoning is found, immediately stop feeding moldy feed and switch to fresh feed.

5. For mildewed cereal feed, soak in 3 times the amount of water for one day and night, and then change the same amount of water for 4 times in a row, most of the toxins can be soaked in clean water, then dried, and then used as feed. If soaking with 10% lime water instead of clean water, the detoxification effect is better.

At present, there is no effective antidote for the treatment, so we can only use symptomatic therapy. Pigs use 25% glucose injection 60 ml, plus vitamin c 10 ml intravenous injection, continuous use for 3-4 days, 50 grams of mung beans, 20 grams of licorice, fried water, put into the sink to allow pigs to drink, at the same time, mix with white sugar, 20 grams per head, twice a day, 7-10 days in a row, has a certain auxiliary effect.