MySheen

Common Fish Drugs 3

Published: 2024-11-21 Author: mysheen
Last Updated: 2024/11/21, Furans are synthetic broad-spectrum antibiotics, many kinds, but only 3~4 kinds are used to prevent and control aquatic diseases. The basic structure of furans is a furan ring with a nitro group attached to the fifth carbon atom. It has strong antibacterial effect. At low concentration, it can inhibit the biological reproduction of various Gram-positive bacteria and negative bacteria; at high concentration, it has bactericidal effect. General bacteria are not resistant to furans, even if they are resistant to sulfonamides and antibiotics.

II. Furans

Furans are synthetic broad-spectrum antibiotics, but only 3~4 kinds are used to control aquatic diseases. The basic structure of furans is a furan ring with a nitro group attached to the fifth carbon atom. It has strong antibacterial effect. At low concentration, it can inhibit the biological reproduction of various Gram-positive bacteria and negative bacteria; at high concentration, it has bactericidal effect. General bacteria are not easy to produce resistance to furan drugs, even to sulfa and antibiotics with resistance to bacteria, furan drugs are still relatively sensitive, but furan drugs are poorly absorbed in the body, absorbed in the body and easy to quickly destroy, blood often can not reach effective blood antibacterial concentration, only in the intestinal tract can maintain effective effect, so in the prevention and treatment of fish intestinal bacterial infection has a good role. In addition, it has recently been reported that furan drugs have carcinogenic effects, so their use has been restricted, and long-term use of such drugs will cause liver and kidney damage in fish.

1. Furazolidone (furazolidone)

[Properties] Furazolidone, also known as furazolidone, is yellow powder or crystalline powder; odorless, bitter taste; almost insoluble in water and ethanol, and slightly soluble in chloroform; decomposed in alkali, dark color under strong light, suitable for sealed storage in the dark.

[Action] This product has low toxicity. Antibacterial spectrum is wide, effective to a variety of Gram-positive and negative bacteria, 5~10 μ g/ml has bacteriostatic effect, 20~50 μ g/ml has bactericidal effect. The drug also has anti-protozoan effect, bacteria are not easy to produce drug resistance to this product, and there is no cross-resistance between sulfonamides and antibiotics. Oral absorption from gastrointestinal tract is small, blood concentration is low, and intestinal concentration is high.

[Usage] This product is mostly used to prevent and treat bacterial enteritis. It is also effective on gill rot, red skin, furuncle, white-headed white mouth, vertical scale, rotten tail, ulcer, vibrio, eel columnar disease and Edwards disease.

[Usage and Dosage] When the feed rate is 4%, the usual dosage is 2.5 g per kg of feed, and the maximum is not more than 5 g. according to a report by japan's tanaka eryo. Control gill rot, red skin, furuncle, white head, vertical scale, ulcer, vibrio disease and so on can be mixed into feed according to the proportion of 0.1~0.2%, made into bait to feed once a day, continuous feeding 3~5 days. Sprinkle 0.3~0.5ppm in the whole pool. Sprinkle should be carried out when the sunlight is weak.

2. Furantoin (furan)

 
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