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Determination of dosage of soft-shelled turtle

Published: 2024-11-05 Author: mysheen
Last Updated: 2024/11/05, 1. Determination of the dosage of drugs for external use (1) the concentration of drugs (ppm) was determined according to the safe concentration of a certain drug and the lethal concentration of the drug to pathogens. (2) accurately measure the volume of turtle pond or determine the volume of bath water. The calculation method of water volume is: water volume (m ^ 3) = area (m ^ 2) × average water depth (m). (3) calculate the dosage: dosage (g) = the concentration of the required drug (ppm, g / m ^ 3) × water volume (m ^ 3) 2.

1. Determination of dosage of drugs for external use.

The main results are as follows: (1) the drug concentration (ppm) is determined according to the safe concentration of a certain drug and the lethal concentration of the drug to the pathogen.

(2) accurately measure the volume of turtle pond or determine the volume of bath water. The calculation method of water volume is: water volume (m ^ 3) = area (m ^ 2) × average water depth (m).

(3) calculate the dosage: the dosage (g) = the concentration of the required drug (ppm, g / m ^ 3) × the volume of water (m ^ 3) 2, and the determination of the dose given internally.

We commonly use the total amount of drugs (mg) and the addition rate of feed drugs (%) as the dosage indicators of oral administration, which are based on the standard dosage. The overall weight and feeding rate of soft-shelled turtles are determined.

(1) Standard dosage: refers to the number of milligrams (mg/kg) of drugs used per kilogram of body weight of soft-shelled turtles, and each drug sold in the market is marked. If you do not know the standard dosage of soft-shelled turtle, it can be calculated with reference to the human dosage and the water solubility of the drug. For example, the adult dosage of sulfonamides is generally 1 g / time, twice a day, with a body weight of 50 kg for adults. 0.04 g per kg body weight Considering the loss of the drug in water, the dosage was increased by 2.5 times (empirical number, generally 2-5 times), that is, the standard dosage per kilogram of soft-shelled turtle body weight was 0.1 g (0.2 g for the first doubling).

(2) the total weight of soft-shelled turtles in the pond (kg) = estimated weight of each soft-shelled turtle (kg) × the number of soft-shelled turtles, or calculated according to the total weight (kg) / feeding rate (%).

(3) feeding rate (%): refers to the number of kilograms of feed per 100 kg body weight of soft-shelled turtles, which is determined according to different culture stages of soft-shelled turtles.

(4) Drug addition rate (%): refers to the number of milligrams of drugs added to every 100 kg of feed. It is obtained from the following formula: standard dosage (mg / kg) × feeding rate (%).

(5) according to the above data, we can get the dose of internal administration from two aspects:

If ① can estimate the total body weight of soft-shelled turtle, then the total dose (mg) = standard dose × total body weight of soft-shelled turtle.

If the daily dose of ② is fixed and has a certain basis, then the total amount of drug administration (mg) = daily dose (kg) × drug addition rate. (this article has been viewed 491 times)

 
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