Prevention and treatment of piglet edema disease

Piglet edema disease is an acute and sporadic infectious disease of weaned piglets caused by hemolytic Escherichia coli. Because the diseased pig mainly shows eye and face edema, conjunctival flushing, it is also known as "red eye disease". And because autopsy shows obvious edema of gastric submucosa and conjunctiva, this disease is called edema disease.

Epidemiology

The disease often occurs at the age of several days after weaning and also occurs in 4-month-old piglets. It is often relatively healthy piglets with high morbidity and mortality. The main source of infection of the disease in infected sows.

Etiology

The main results are as follows: 1. Bacteria-carrying feces pollute feed, drinking water and environment, and directly pollute through digestive tract after ingestion.

2. After weaning, if the feed is too simple, the protein content is too high, and there is a lack of vitamins and minerals, it is easy to lead to malnutrition, disorder of microflora in the body and mass reproduction of Escherichia coli, resulting in the occurrence of edema disease.

3. Stress factors (group conversion, transportation, climate change, etc.) will also cause the occurrence of the disease.

Clinical symptoms

Piglets have a sudden onset of disease, at the beginning, diarrhea or fecal secretion, 1-2 days later, the course of disease suddenly accelerated or died. Sick pig limbs are weak, ataxia, some sick pigs kneel on the front legs, hind legs upright, suddenly jump forward, capture, suddenly fall to the ground, limbs to do swimming-like sliding. Sick pigs with mild illness, depressed spirit, loss of appetite or abstinence, most of the body temperature is not high.

Autopsy examination of pathological changes

1. Autopsy is common in facial, conjunctival and gingival subcutaneous edema, showing gray-white cool powder-like edema.

2. Gastric wall edema is common in the great curvature and cardia, and there are different layers of gel-like edema between the mucous layer and the muscular layer.

3. Some diseased pigs often have edema in mesentery, rectum, gallbladder and throat.

4. There are diffuse bleeding changes in small intestinal mucosa.

5. Mesenteric lymph nodes are congested and even bleed.