Prevention and treatment of oral sore in sheep

Sheep aphtha, also known as sheep contagious pustule, is a contagious disease of sheep and goat caused by virus. it is characterized by papules, blisters, pustules and verrucous scab formed in lips, tongue, nose, breast and other parts. the antigenicity of viruses isolated from different regions is not completely consistent, so let's take a look at the prevention and treatment of sheep aphtha.

Clinical symptoms of sheep aphthous ulcer

1. Sick sheep: diseased sheep have decreased appetite, low spirits, warm mouth, red and swollen gums. Small erythema scattered around the eyes, mouth, upper lip and nasal mirror, erythema gradually turned into papules and small nodules, and then into blisters and purulent vesicles, which formed yellow or brown verrucous scabs. After 1 week and 2 weeks, the crusts of the mild disease were dry and exfoliated, leaving erythema, and in severe cases, ulcers of different sizes appeared on the gum, tongue and buccal mucosa, and then papules, blisters, pustules and scabs were formed and fused with each other to form a large area of scab. The scab continues to thicken, the scab is accompanied by granulation tissue proliferation, the whole lip of the diseased sheep is swollen, everted, showing a mulberry-like uplift, seriously affecting feeding.

2. Dead sheep: dead goats are extremely emaciated, with black scabs on the lips, extending to the face, blisters, ulcers and erosion in the mouth, subcutaneous bleeding spots on the face, scabs and ulcers on the corners of the mouth, lips, tongue, etc., trachea ring bleeding, hyperemia, lung congestion, swelling, darkening of color, myocardial and epicardial bleeding, thinning of the small intestinal wall, mild bleeding, and no characteristic changes in other parts.

Preventive measures of oral sore in sheep

1. In the endemic area of the disease, the attenuated vaccine strain which is the same as the local epidemic strain can be used for immunization. Through the method of continuous passage of calf testicular cells, Gansu Provincial Animal Husbandry and Veterinary Research Institute of China, the attenuated strain was made into freeze-dried live vaccine, which is suitable for scratches on the mucous membrane of the lower lip of sheep and goats of all ages, with an inoculation dose of 0.2 ml per head. It can also be inoculated on the skin scratches on the medial thigh. The immunity period is 3 months. When used in a large area in the field, the protection rate is more than 80%.

2. The scab of naturally diseased sheep can also be collected in the endemic area of the disease, and 1% of the virus solution can be made with 50% glycerol saline buffer after grinding, and then scratched and inoculated at the hairless tail root of healthy sheep. Inflammation or pustular lesions occur after about 7 days of inoculation, followed by scab, and the crusts fall off after a few weeks. This method of immunity can produce lasting immunity. The vaccination of ewes should be completed 3-4 weeks before delivery. This method is in danger of detoxification, so it is only used in epidemic areas.

Treatment of sheep aphthous ulcer

1. Hara (marmot) oil 1kg is melted and mixed with 300g trichlorfon. The affected part can be cured after 1 day. More than 12000 sheep have been treated with this method, and all of them have been cured.

2. Ribavirin (trichlorazole nucleoside injection) 100mg / ml, dexamethasone injection 5mg / ml, mixed intramuscular injection at 2:1, adult sheep 3ml, lamb reduced by half or 2ml, locally smeared with iodoglycerin or gentian purple. The general use of drugs for 2 to 3 days, the effect is better, the cure rate is high. In severe cases, penicillin and streptomycin should be used twice a day.

3. Disinfect the scissors and camera to remove the scab and pustular skin, disinfect the wound with Qiangxiaoling solution, mix the ice boron powder (borneol 50g, borax 500g, Yuanming powder 500g, cinnabar 30g, research powder, mix well) into a paste, foam the affected part, apply the medicine once every other day, use 2 times for 3 times in a row, treat the scab or scab for 10 days, until the scab or scab falls off. A total of 20 cases were treated and all were cured.

4. The wound can be smeared with the following drugs: 2% gentian purple or 3% iodine tincture glycerin (3 grams of iodine, 5 grams of potassium iodide, 10 milliliters of 75% alcohol dissolved and 10 milliliters of glycerol) or iodine pine mixture (1 part of iodine tincture, 1 part of pine distillate oil, 1 part of paraffin oil), twice a day for 3 days.

5. After scab removal, the wound is washed with 0.1% potassium permanganate, then mixed with a mixture of 3% iodine tincture, pine pomegranate oil and paraffin oil (1:2:2), or iodine glycerin (70 ml of 7% iodine tincture and 30 ml of anhydrous glycerol), once a day for 7 consecutive days, and then proceed to the next course of treatment every 3 days.

6. Ulcer surface coated with traditional Chinese medicine

① Bletilla powder, vegetable oil, borneol (10:5:1) mixture, mix well.

② people in white, artificial bezoar, indigo, borneol, gypsum, catechu and other portions, a total of the end.

③ Qingdai 9g, Phellodendron chinense 9g, Coptis chinensis 6g, Platycodon grandiflorum 6g, catechu 6g, peppermint 3g.

④ Koujiling: use Qingdai, Phellodendron Phellodendri, Di Ding, withered alum, hundred herbs decoction and so on to research into fine powder and adjust it into paste with water.

⑤ catechu 15g, withered salt 12g, human Zhongbai 9g, Chuanlian 9g, flying alum 9g, Qingdai 6g are applied or sprayed into the oral cavity. The above drugs are applied once or twice a day, wipe off the hard scab with cotton dipped in 50g / L copper sulfate solution, and then apply iodized glycerin (50g / L iodine 100ml, glycerin 100ml) to the affected area.