Piglet paratyphoid fever and its treatment

Piglet paratyphoid is an infectious disease of piglets caused by porcine cholera and Salmonella typhimurium, which mostly occurs in 2-4-month-old piglets. The acute cases were septicemia, and the chronic ones were necrotizing inflammation of large intestine and pneumonia.

Popular characteristics

Paratyphoid fever of piglets mostly occurs in 2-4-month-old piglets with poor sanitary conditions, showing local epidemic or distribution, and the epidemic is slow, especially in cold and changeable climate and continuous rainy season. In addition, wet, crowded, long-distance transportation, parasitic diseases, early weaning, castration and so on can promote the occurrence of the disease.

Clinical characteristics

1. Acute type (septic type)

It is common in piglets shortly after weaning, with elevated body temperature (41mur42 degrees Celsius), loss of appetite, chills, and often stacked together. Dysentery after constipation at the beginning of the disease, faeces yellowish or grayish green, stench, sometimes bleeding, the belly, ears and limbs skin showed dark red or cyan spots in the later stage. The diseased pigs had difficulty breathing and their body temperature dropped, and usually died after 2 Mel for 6 days.

2. Chronic diseases (colitis type)

This type is common, similar to intestinal classical swine fever, gathering, shivering, viscous or purulent secretions in the eyes, constipation and diarrhea occur, feces are grayish green, smelly, mixed with blood. The diseased pig is thin, often hangs himself in the abdomen, screams on the back, and seems to have symptoms of abdominal pain. Scab-like eczema appears on the abdominal skin. Some sick pigs cough and their body temperature rises slightly. The course of the disease is 2mi for 3 weeks or more, and the undead have dysplasia or relapse later.

Autopsy examination of pathological changes

1. Acute type

Mainly septicemia changes, spleen significantly enlarged, the edge is obtuse, dark with blue, feel soft when touching pressure, similar to rubber, section blue-red, you can see enlarged lymphoid follicles. Mesenteric lymph nodes are corded and enlarged, other lymph nodes are also enlarged, soft and red, serous inflammation and bleeding, similar to marble. The liver and kidney also have varying degrees of swelling, congestion and bleeding. The mucous membrane and serosa of the whole body had bleeding spots in varying degrees, and the blood stasis in the extremities was bluish purple.

2. Chronic type

The characteristic lesion is necrotizing enteritis: cecum, colon or part of the posterior ileum, the intestinal wall is thickened, the mucosa is covered with a layer of diffuse necrotic substance, grayish yellow or light green bran-like substance, peeled off to see the bottom red, the edge has an irregular ulcer surface. Some of the mucosa around the follicles were necrotic. When necrosis develops to the deep layer, it can cause fibrinous peritonitis. The mesenteric lymph nodes were swollen with partial caseous degeneration. The spleen is slightly swollen. The enlarged part of the lung showed grayish red, some showed cheese-like changes, and there were small grayish-yellow nodules on the sections. if secondary Pasteurella multocida or suppurative cell infection developed into hepatoplastic areas or thickened foci.

Bacteria isolation

Acute cases can be isolated and identified by using liver, spleen and other disease materials. Immunofluorescence test can also be done.

In a word, the diagnosis can be diagnosed by comprehensive analysis based on the above characteristics.

Prevention and control scheme

The main results are as follows: 1. Improve the feeding management and sanitary conditions, and give high-quality and full-price pellet feed to enhance the disease resistance of piglets.

2. Vaccination or oral vaccination should be carried out in the areas where the disease occurs frequently or in pig farms.

3. After the onset of the disease, the sick pigs should be isolated and treated, and the contaminated pig houses should be thoroughly disinfected / tolerated pigs should be isolated and fattened and eliminated. Pigs that die of illness are forbidden to eat! Guard against poisoning! For pigs without disease, adding 100 grams of chlortetracycline or 100 grams of sulfamethazine to each ton of feed has a preventive effect. The treatment drugs can be chloramphenicol (100 mg per kilogram of body weight per day, taken 3 times per day; intramuscular injection, 10 milligrams per kilogram of body weight per day, injected 3 times), furazolidone (20 milligrams per kilogram per day, orally taken twice, after 3-5 days, the dose is halved, and then taken 3-5 days).