Prevention and treatment of Porcine epidemic diarrhea

Porcine epidemic diarrhea is a contagious intestinal infectious disease caused by porcine epidemic diarrhea virus. It is characterized by vomiting, diarrhea and dehydration. Its clinical changes and symptoms are very similar to those of porcine infectious gastrointestinal tract. The disease first occurred in England in 1971 and occurred one after another in China in the early 1980s. it mostly occurred from December to January to February of the following year in China, and it was also reported in summer in pigs of any age. the younger the age, the more serious the symptoms and the higher the mortality.

Symptoms of porcine epidemic diarrhea

The incubation period of porcine epidemic diarrhea is generally 5-8 days, and the incubation period of artificial infection is 8-24 hours. The main clinical symptoms are watery diarrhea or vomiting between diarrhea. Vomiting often occurs after eating or feeding. The severity of symptoms varies with age, the younger the age, the more serious the symptoms. Three to four days after diarrhea occurred in newborn piglets within a week, they died of severe dehydration, with a mortality rate of 50% and the highest mortality rate of 100%. Diseased pigs have normal or slightly higher body temperature, depressed spirit, loss of appetite or abstinence. Weaned pigs and sows often show mental fatigue, anorexia and persistent diarrhea for about a week, and gradually return to normal. A few pigs were stunted after recovery. All fattening pigs developed diarrhea after being raised in the same circle and recovered a week later, with a mortality rate of 1: 3%. The symptoms of adult pigs were mild, some only showed vomiting, and the severe watery diarrhea could be cured within 3-4 days.

Prevention of epidemic diarrhea in pigs

1. To strengthen nutrition and control mycotoxin poisoning, a certain proportion of mildew remover and high-grade vitamins can be added to the feed.

2. Raise the temperature, especially with huai house, delivery room and nursery. The ambient temperature is not less than 15 ℃, 23 ℃ in the first week before parturition, 25 ℃ in the first week of delivery, 2 ℃ in the first week, 28 ℃ in the first week, and 2 ℃ in the first week to 22 ℃. The small ambient temperature in the delivery room is 32 ℃ in the first week and 2 ℃ in the next week. The drinking water temperature of pigs is not lower than 20 ℃. The sows before delivery for more than 2 weeks were driven into the delivery room, and the delivery room was heated ahead of time.

3. Do pig farm health care regularly, and keep the whole pig herd healthy once a week every month to control the growth of bacterial diseases. For the health care of sows and 3 injections of health care for piglets, the first injection of high fever gold needle can be selected. On the day of giving birth, sows are injected with 10ml / 20ml, and if infected, 10ml ~ 20ml / piglets are injected 3 days after parturition. Piglets were injected with 0.5 ml, 0.5 ml and 1 ml intramuscularly at 3, 7 and 21 days after birth, respectively.

4. The breeding pigs were urgently inoculated with gastric flow double vaccine or gastric flow wheel triple vaccine, and immediately sealed off the disease area and delivery room after vomiting and diarrhea. Culling piglets with vomiting and watery diarrhea within 10 days of age is a way to cut off the source of infection and protect susceptible pigs.

Treatment of Porcine epidemic diarrhea

1. Vomiting diarrhea pigs from 8 to 13 days old were treated with oral rehydration salt mixed with oxytetracycline or norfloxacin for about 39 ℃, 4 ~ 5 times a day to ensure no dehydration.

2. Sick pigs must be strictly isolated and must not spread. At the same time, drugs should be used for adjuvant treatment. The recommended scheme: high fever gold needle + concanavalin, which will get better results after 5 days.

3. The treatment of this disease with antibiotics is ineffective, so we can refer to the prevention and treatment of transmissible gastroenteritis in pigs. In the endemic area of the disease, pregnant sows can be artificially infected with feces or small intestinal contents of diseased pigs 2 weeks before delivery to stimulate them to produce milk-derived antibodies so as to shorten the epidemic of the disease at home.

4. China has developed an inactivated PEDV formaldehyde aluminum hydroxide vaccine with a protection rate of 85%, which can be used to prevent the disease. PEDV and TGE double inactivated vaccines were also developed. The two vaccines immunized pregnant sows and suckling pigs were protected by colostrum. Vaccination of piglets at home weaning could reduce the incidence of these two diseases.

① was inoculated with bivalent bacteria of transmissible gastroenteritis and epidemic diarrhea in pigs. When pregnant sows were vaccinated one month before delivery, piglets could be passively immunized by breast milk. It can also be immunized with attenuated or inactivated vaccine against porcine epidemic diarrhea.

② leukocyte interferon 2000-3000 international unit, once or twice a day, subcutaneously injected.

⑧ oral rehydration salt solution 100ml to 200ml, one oral.

④ anisodamine hydrochloride, 5 ml for piglets and 20 ml for big pigs, once a day, injected at Houhai acupoint.

⑤ was treated with antibiotics (tetracycline and gentamicin) to prevent secondary bacterial infection.

⑥ prescription of traditional Chinese medicine: Codonopsis pilosula, Atractylodes macrocephala, Poria cocos 50 grams each, Euphorbia officinalis, patchouli, roasted ginger, licorice 30 grams each. Add 200 grams of sugar to the juice and feed it with a small amount of feed.