Diagnosis and treatment of cysticercosis in rabbits

Rabbit cysticercosis is a kind of tapeworm disease caused by canine lenticular cysticercus or canine continuous polycysticercus parasitized in the greater omentum, liver, mesentery and abdominal cavity of rabbits. This disease is a common parasitic disease in rabbits. It has a wide range of diseases and a high infection rate, but it rarely kills rabbits. It is often found in clinical autopsy. In mild infection, there are no obvious symptoms, but in severe infection, it can hinder the growth of rabbits, may also cause death, and bring certain economic losses to the production of rabbits. In February 2007, a company in Jinan introduced a batch of adult rabbits, some of them had abdominal swelling and came to our hospital with anti-inflammatory drugs with no effect. The diagnosis of rabbit lenticular cysticercosis was made. The results are reported as follows. 1. Morbidity and clinical symptoms the company introduced a batch of adult rabbits in January 2007. A few days later, a number of rabbits showed varying degrees of mental depression, some had diarrhea, some had abdominal swelling, and often died sporadically. depressed spirit before death. The specific manifestations of diseased rabbits are loss of appetite, abdominal distension, enlarged abdominal circumference, mild diarrhea, lethargy, depression of spirit, paleness of visible mucosa, progressive weight loss, rarely death, and death is mostly caused by extreme failure. After the onset of the disease, rabbits used ciprofloxacin, sulfonamides and so on, but the effect was not good. 2. the pathological changes of the rabbits were in poor nutritional status, and there were no eye lesions in the heart and lungs; there were many fibrous marks on the liver (caused by the migration of six-hook cercariae to the peritoneum); the stomach, kidney and spleen were basically normal, and there were thin chyme and juicy in the small intestine; peritoneal effusion, yellowish, poor coagulation The main abnormalities are that there are some mung bean-sized cysts in the greater omentum and mesentery, which are connected in strings near the connective tissue, the cysts are oval or round, and the cyst wall is a thin film. The translucent cyst fluid and milky white larval nodules of rice grains are broken. 3. Laboratory examination 3.1 the cystic content was placed on the slide to make a pressing tablet. Under a 10-fold microscope, it was found that the front end of the cysticercus was a scolex, on which there were four round suckers and apical processes, and there were two rows of horny hooks on the apical process. 3.2 Bacteriological examination: the rabbit heart and liver were aseptic and inoculated on the serum medium. 37 ℃ for 24 hours and 72 hours, there was no bacteria-free growth. 3.3.The liver and spleen of the rabbits examined by virological examination were ground into 1 ∶ 5 suspension, frozen and thawed repeatedly for 3 times, centrifuged with 4000rpm for 20 minutes, and the supernatant and human type O blood were taken for hemagglutination test, the tested samples were negative and the rabbit plague samples were positive in the control test, which can rule out the infection of rabbit plague virus. 4. According to epidemiology, clinical symptoms, autopsy changes and laboratory examination, the rabbit group can be diagnosed with lenticular cysticercosis. 5. The whole group was fed with Qilu insecticidal mixture with 800g per ton (1000kg) feed for 7 days. After 5 days, the mental state of the rabbits improved obviously. 7 days later, a marked sick rabbit was killed and it was found that lenticular cysticercosis had disappeared and its remains could be found on the greater omentum, but it was difficult to distinguish. 5.2 lenticular cysticercosis is mainly caused by improper management and should be prevented. First of all, self-raised dogs in rabbit farms should be dewormed regularly to prevent dogs from entering the rabbit farm, especially in the feed room and rabbit house. Secondly, rabbits should be regularly dewormed, insecticidal, each ton of feed added 300m / 500g, continuous use for 7 days, once every 2 months. Praziquantel was given orally at a dose of 100 mg per kilogram of body weight and again in 24 hours. Finally, the waste of rabbits should be disposed of properly, and it is absolutely forbidden to feed the viscera of dead rabbits to dogs, which can reduce human transmission. In addition, do a good job in the environmental hygiene of the rabbit farm, all kinds of appliances and facilities are often disinfected, and the field should also do a good job of rodent prevention and disinfestation to prevent pathogens from entering the rabbit farm. 6. Discussion 6.1 although the fatality rate of rabbit cysticercosis is low, the infection rate is high, the speed of transmission is very fast, and it is difficult to cure completely, and the growth and development of diseased rabbits is slow, emaciated and frail, the resistance is decreased, and the feed reward is low, which causes certain economic losses to farmers. The majority of farmers should attach great importance to the prevention of the disease. 6.2 because farmers also have the habit of deworming rabbits, it is generally believed that there will be no internal parasitic diseases. However, the survey found that most of the insect repellents used by farmers are nematodes, which have almost no effect on worms such as tapeworms and trematodes. Although insect repellents have been used many times, helminthiasis still occurs. Therefore, it is suggested that different kinds of drugs should be used in different stages of the rabbit farm to achieve satisfactory deworming effect. 6.3 deworming is a consistent method of deworming in many farms, but the disadvantage of this method is that it is not seen in the feces of many parasites, so it is inevitable to use medicine when the disease occurs. 6.4 for deworming in rabbit farms, I suggest that paraquat should be used together with ivermectin, both internal and external, larvae and adults, and the effect is more obvious. Why is there no one sitting on the sofa? Grab one-is the death rate serious? -- Cysticercus lentiformis [special spot] Cysticercus lentiformis is parasitic in the organs of rabbits and is spherical. After the rabbit ate the feed contaminated with lenticular cysticercus eggs, the six-hook metacercaria drilled out of the egg shell, entered the blood vessels of the intestinal wall, followed the blood flow to the liver, and began to develop. After 15-30 days in the liver, it drilled out of the liver capsule and entered the abdominal cavity. In the mesentery, gastric omentum and other places to grow and develop into lenticular cysticercus. [symptoms and pathological changes] 1, a large number of infections such as hepatitis and digestive disorders, such as loss of appetite, abdominal distension, mental depression, chronic emaciation and so on. Subcutaneous edema often occurs and there is more fluid in the abdominal cavity. 2, severe chronic cases can see hepatomegaly, sclerosis, mesentery, omentum, liver surface, how many different lenticular cysticerci. Sometimes as many as dozens or hundreds of cysticerci, shaped like grape bunches [prevention measures] prevention: to prevent dog and cat feces from polluting rabbit feed and drinking water. Treatment: suspicious cases were treated with chlorpromazine, intramuscular injection, 0.1~0.2ml/kg for 5 days. If necessary, please contact: 13203806202