Talking about the secondary disease of Pasteurella multocida

In recent years, many rabbits in rabbit factories (households) have rapid diarrhea, and their anus and hind limbs are contaminated by black dung. Due to the acute onset of the disease and the short course of disease, they often die without time for treatment. Its symptoms are similar to Clostridium welchii; some young rabbits died of abdominal distension, refusal to eat and shortness of breath. After dissection, it was found that almost all the dead rabbits had severe congestion and congestion in the lungs, accompanied by edema symptoms; gastric mucosal exfoliation, ulcers, common cases of gastric rupture; small intestinal congestion, black thin stool in the cecum, often accompanied by gas. The dead rabbits are breeding rabbits, young rabbits, and even lactating young rabbits. In particular, the young rabbits showed dyspnea, mucopurulent secretions and crusts around the nasal cavity. Secretions or crusts clog the nostrils, making breathing more difficult, sick rabbits lactation is greatly reduced or eliminated, the body is thin, dry and black death. Facing the clinical symptoms of diarrhea and abdominal distension in rabbits, many people are diagnosed as Escherichia coli or Clostridium welchii caused by feed mildew. The first choice is antibiotic treatment, generally using Shijing, norfloxacin and other drugs injection or Qingda, quinolinol oral, the treatment effect is not ideal. Some diarrhea stopped, but because of bloating belly distension, waste food, mental depression died; some injection is ineffective, abdominal effusion (bladder generally no urine). Numerous cases tell us that in production practice, we take measures to deal with Pasteurella multocida, but every time we get the effect that pasteurellosis is a conditional pathogen, once rabbits are stimulated by various stress factors, can reduce the body resistance and disease. Such as: the general cold of rabbits, due to the breeders' negligence and delay the best time for treatment, resulting in the longer the onset time, the more complications, the difficulty of treatment is also increased accordingly. It is generally common for rhinitis, showing chronic development. At the initial stage of the disease, the systemic symptoms of the diseased rabbits were still good, and only clear nose flowed continuously from the nostrils, but there was no timely treatment at this time, clear nose gradually turned into purulent nose, purulent nose became yellow and thick nose, and secretions seriously blocked the nostrils. When you see sick rabbits cough, sneeze and then turn to pneumonia. The sick rabbit began to lose appetite and depressed spirit, and at this time most breeders thought of the treatment, but because of the improper methods, means and drugs, the condition often did not get better, and then blindly increased the dosage of drugs, resulting in drug poisoning. The liver of the dead rabbit is black and purple. Some people also paid attention to the treatment at the initial stage of the attack of the rabbit, but the treatment was not thorough. When they saw that the diseased rabbit no longer had a runny nose, they thought they were cured, so they gave up the opportunity to continue the treatment so that they could be cured completely. On the contrary, the disease broke out repeatedly, and the sound of "coughing" kept coming out in large groups. Because rabbits use excessive drugs, it is easy to cause chronic poisoning, and the result is that not only the absorption rate of drugs is low, but also it is very easy to cause a vicious circle, which makes the body's resistance worse and worse. in the end, it leads to the phenomenon that the condition becomes more and more serious and the loss is greater. Most rabbit breeders know that the four most common diseases in rabbit breeding: rabbit plague, coccidiosis (diarrhea), skin disease and pasteurellosis. At present, except for pasteurellosis, the other three diseases have good epidemic prevention measures. as long as the breeders can inject the rabbit vaccine on time, according to the dose, and give the corresponding drug prevention according to the feeding process, it can basically be well solved. However, with the continuous expansion of the scale of rabbit breeding, the mode and facilities of management are relatively backward, and the incidence caused by the lag of management is on the rise, especially respiratory diseases. At present, there are no effective epidemic prevention measures for respiratory diseases in rabbits, so they have suffered heavy losses. We believe that most of the causes of respiratory diseases in the rabbit industry are due to stress factors such as colds, rhinitis, improper feeding or sanitary conditions and lack of hardware facilities, which can easily lead to the decline of the physique and resistance of rabbits. as a result, Pasteurella multocida, which exists in the mucous membrane of the upper respiratory tract and tonsil, propagates in large numbers, invades the lower respiratory tract and causes lung lesions. Due to the strong pathogenicity of Pasteurella multocida, it is easy to cause secondary infection of digestive tract and reproductive tract, resulting in different degrees of clinical symptoms and pathological changes in digestive tract and reproductive tract, forming multiple organ infection and promoting the morbidity and death of a large number of rabbits. In addition, the amount of corn added to the feed of some farmers is more than 20%, and some are even about 30%. Corn contains 25% crude fiber and 72% starch, which is digested slowly in the small intestine. After suffering from respiratory disease, the gastrointestinal digestion function of rabbits slows down, and the peristalsis is very slow. coupled with this high content and slow digestion, it can lead to an increase in the amount of starch entering the hindgut, promote the reproduction of digestive starch bacteria, and produce a large number of acidic substances. cause changes in the microbial area and the increase of pathogens, a large number of volatile fatty acids produced by fermentation increase the osmotic pressure of the hindgut, suck water out of the blood, resulting in diarrhea. Under normal circumstances, there should not be high starch in the hindgut because most of them have been absorbed in the small intestine. when these undigested starch enters the hindgut, they provide abundant fermentation substrates for microorganisms. the toxins they produce cause diarrhea or abdominal distension, resulting in the death of rabbits. To sum up, the symptoms of bloating and diarrhea in rabbits should be judged accurately first in order not to delay the treatment time and to prescribe the right medicine. Our practices are as follows: 1. Take frequent epidemic prevention for female rabbits. Due to the increase of culture density, the pollution of culture environment is becoming more and more serious, and many bacterial diseases and viruses are becoming more and more difficult to control. Pasteurellosis is a typical example. Although the breeding rabbits were given Babo vaccine every four months, the protection rate was low. Due to the needs of breeding and production, the body condition of the female rabbit continues to decline, the immune function of the body is relatively poor, and the ability to resist bacteria will also be reduced, so according to the advice of experts, after each pregnancy is confirmed, the female rabbit will be injected with 2ml Babo vaccine. The aim is to improve maternal antibodies to ensure that young rabbits do not die of respiratory diseases during lactation. 2. To give priority to "prevention" and strengthen feeding management. For the prevention of respiratory diseases, the rabbits in each growing period are mainly prevented by traditional Chinese medicine in addition to regularly making Babo combined vaccine. Qingwen Baidu Powder, a traditional Chinese medicine preparation, is regularly added to the feed to achieve the purpose of clearing heat and detoxification, resolving phlegm and relieving cough, relieving asthma and inhibiting virus replication. 3. Insist on rabbit disinfection. In the case of the presence of rabbits in the rabbit house, all items in the rabbit house (including the rabbit body) and the space are sprayed with a certain concentration of disinfectant. Rabbit disinfection can not only effectively kill all kinds of bacteria and viruses floating in the rabbit house, reduce the floating dust in the rabbit house, but also kill the harmful microorganisms in the cushion and reduce the production of harmful gases such as carbon dioxide and ammonia by fermentation. purify the air in the rabbit house, so as to effectively prevent the occurrence of respiratory diseases caused by Escherichia coli and mycoplasma. In the high temperature season in summer, rabbit disinfection can reduce the house temperature by 3-4 degrees, prevent heat and cool down the rabbits, and effectively reduce heat stress. 4. Do a good job of three frontiers and two borders. The so-called "three channels" refers to the respiratory tract, digestive tract and reproductive tract of the rabbit; "two borders" refers to the internal and external environment of the rabbit body. In order to ensure the normal function of the rabbit "three channels", we must solve the big environment of rabbit life, such as rabbit house, cage, ventilation, light …... And so on, because the biological transformation in rabbits needs the cooperation of environment; it directly affects the physical function of rabbits, thus affecting the growth and development and breeding of offspring. The internal environment of the rabbit body: circulatory system, nervous system, motor system, digestive system, respiratory system, genitourinary system; body temperature, blood pressure, humoral indicators. We can only start from the two frontiers, comprehensively control and master the whole process of production, establish and improve various management systems and feedback mechanisms, take the whole picture of production, and arrange production plans reasonably. Otherwise, it will cause "three diseases" due to the influence of "two borders", lead to economic losses and affect the normal progress of production. At the same time, once the rabbit has a problem, it can be sorted out from the clues of "three ways" or "two borders". It is easy to find the key points of the problems, so as to improve the management level of breeders. 5. To establish a group of rabbits without Pasteurella multocida. Through selection and identification, breeding rabbits without Pasteurella multocida were selected to establish core group and basic group. Adhere to self-breeding and self-support. At ordinary times, we should strengthen feeding management and strictly prohibit livestock and poultry from entering the rabbit farm, so as to put an end to or reduce the source of infection. The rabbits must be examined regularly, and the rabbits with purulent conjunctivitis, otitis media, runny nose, sneezing and moist nose hair should be isolated, raised and treated in time, and chronic cases should be eliminated at any time. -- collected it, thank you! Adhere to rabbit disinfection, this method is good Donglong on 2009-11-17 16:46 add the following content insist on rabbit disinfection, this method is good