MySheen

Type 4 allergy can increase pulmonary capillary permeability.

Published: 2024-11-22 Author: mysheen
Last Updated: 2024/11/22, Allergy and hypersensitivity have the same meaning, that is, allergy, which means that the autoimmune system is too sensitive to pollen, animal fur, smoke and dust, and causes damage to the body. This allergic reaction is called anaphylaxis package.

Allergy and hypersensitivity have the same meaning, that is, allergy, which means that the autoimmune system is too sensitive to pollen, animal fur, smoke and dust, and causes damage to the body. This allergic reaction, that is, allergic reaction, includes allergic reactions such as skin, respiratory tract and digestive tract. People with allergies are also easy to be allergic to certain parasites. When they come into contact with an allergen one after another, they have allergies and allergic or hypersensitive reactions.

There are four types of hypersensitivity or allergy: type I rapid type, type II cytotoxic type / cytolytic type, type III immune complex type, type IV delayed type or cell mediated type and so on. Type I is the most common type of rapid onset, allergic reactions are mainly reflected in the surface, such as respiratory tract allergic asthma, digestive tract allergic gastroenteritis, as well as skin eczema, and scratches, atopic dermatitis, skin pruritus and so on.

The cytotoxic antibody reaction of type II has a strong correlation with blood, such as blood type inconsistency during blood transfusion, neonatal hemolytic anemia, autoimmune hemolytic anemia and so on. Type III immune complex allergy is caused by antigen-antibody complex and is strongly related to blood vessels and kidneys. Specifically, in circulation, medium-sized molecular immune complexes are deposited in the vascular wall, glomerular basement membrane or tissue space, activating complements and causing inflammation, such as nephritis and other nephropathy, systemic lupus erythematosus, arthritis and myocarditis.

Type IV is mediated by specific sensitized T cells, which is mainly reflected in the local inflammatory response and changes slowly. generally, there is a strong reaction only after 24-48 hours of local inflammation, so it is also known as delayed hypersensitivity. This is because after the encounter between the antigen and the body, T cells will be transformed into sensitized lymphocytes, making the body allergic. After the invasion of the same antigen, T cells differentiate, proliferate, release numerous lymphokines and form an inflammatory reaction. Specific such as tuberculosis, measles, and so on.

 
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