Diagnosis and treatment of a Gosling plague

Gosling plague is caused by Gosling plague virus, which is an acute infectious disease of goslings. With the continuous increase of breeding quantity and density, the goslings after hatching for 3 days or even 20 days are easy to develop the disease. If the prevention and control work can not keep up, it will cause serious economic losses to the farmers.

1 morbidity

A farmer in our township bought 3000 goslings on March 15, 2012. On the 6th day, the goslings died of unknown causes, 810 / d. After that, it was found that the goslings were mentally depressed, shrinking their heads, dozing, loss of appetite, diarrhea, discharge of gray-white or yellowish-green sparse feces with bubbles, and the death toll was increasing. Enrofloxacin and ribavirin were not effective at first, then Gosling plague serum was injected in large doses, and the disease was controlled.

A total of 630 rats died at the age of 20 days.

2 clinical symptoms

Within 1 week of age, the infected geese often show the most acute type, and usually have no early symptoms. Once the disease occurs, it is extremely weak or falls to the ground, and dies soon. Most of the cases occurred in the second week were acute type, in which the goslings were mentally stunted, shrank, walked off the group, dozed, lost appetite, and then became obsolete and liked water; dyspnea, viscous secretions from the nostrils, darkening of beak tip and web color; crop has a large amount of gas and liquid, severe diarrhea, discharge of gray-white or yellowish-green thin feces with air bubbles, a few strip sausage-like feces with fibrous pseudomembrane on the surface. Diseased geese often have neurological symptoms before death, including head and neck torsion, foot paralysis and systemic convulsions. He died in 1 to 2 days. Most of the cases over 2 weeks old were subacute, with mental fatigue, diarrhea and emaciation as the main symptoms, and the case fatality rate was generally less than 50%. Most of the tolerant geese showed growth inhibition and feather shedding over a period of time, and a few sick geese could recover naturally.

3The change of dissection.

The diseased goose showed systemic septicemia; the liver was enlarged and brittle; the kidney was slightly enlarged and dark red, with urate deposition in renal tubules; the pancreas swelled light red, with occasional gray-white nodules; the heart developed acute heart failure, the myocardium was dark and dull, showing characteristic pallor; perianal adhesion of thin feces, dilatation of cloacal cavity, thin fluid from mouth and nose, brown mucosa; dry conjunctiva, dehydrated skin all over the body, skin dehydration.

The lower tissue is significantly congested; meningeal vascular congestion and hemorrhage; the crop is empty and there is a large amount of water in the stomach. The characteristic lesion is acute catarrhal and fibrinous necrotizing enteritis in the small intestine (jejunum and ileum). The typical change is the necrosis and exfoliation of the whole intestinal mucosa in the middle and lower end of the small intestine, which forms an embolism with the coagulated cellulose exudate; the surface of the intestinal content wraps the capsule and blocks the intestinal cavity. The ileocecal segment is dilated, solid, about 2~5cm, shaped like a sausage, and all the intestines are filled with grayish or yellowish embolism. The intestinal wall became thinner and did not form ulcers, and some of the intestinal mucosal surfaces attached scattered fibrinous clots without forming bands or embolism.

4 diagnosis

According to the epidemic characteristics that the disease only causes goslings, combined with the appearance of severe diarrhea and neurological symptoms and the characteristic acute catarrhal and fibrinous necrotizing enteritis in the small intestine (this characteristic embolism has been considered to be a characteristic lesion of Gosling plague), a preliminary diagnosis can be made. The diagnosis of this disease needs to be confirmed by virus isolation and identification or serum specific antibody test.

5Prevention and treatment

Isolate the seriously sick geese from the lightly diseased geese, thoroughly disinfect the flume, material trough and the environment in the house, strengthen the feeding and management, and bury the sick and dead geese deeply. The whole flock of geese were immediately injected with Gosling plague high immune serum, and each goose was injected subcutaneously with 2 mL of pyrrolidine for 3 days and then injected again. At the same time, electrolytic multidimensional and large amounts of vitamin C were used to enhance the body's resistance and prevent stress reaction, and were treated with anti-inflammatory drugs. After treatment, the condition of the goslings was fully controlled at the age of 20 days, and no more death occurred. The climate of our province is cold, and it is spring to start raising goose chicks, so it is necessary to do a good job in the prevention of Gosling plague. Adult geese can carry virus and detoxify but not get sick, and can become a source of infection, so there should be a certain distance between goslings and adult geese to avoid direct contact with diseased geese or to eat contaminated feed and drinking water. After the occurrence of Gosling plague, isolation should be strengthened and reared in groups.

Goslings can be injected with anti-Gosling plague serum or highly immunized yolk antibody, each with subcutaneous injection of 1.0~1.5mL, and those with symptoms should be injected with 2~3mL, and the dosage of goslings over 10 days old should be increased. In addition, electrolytic multi-dimension, minerals and antibiotics should be added to feed or drinking water. The recovered geese have strong immunity. The anti-Gosling plague serum prepared by adult geese can be used to treat and prevent the disease. The newly hatched goslings can resist the infection of the virus after injecting anti-Gosling plague serum. In addition, Gosling plague vaccine can also be used. All appliances and equipment used for hatching in the hatchery must be cleaned and disinfected after each use. The acquired eggs had better be fumigated with tertiary concentration of formaldehyde to 20min. If it is found that the goslings get sick in 3 to 5 days, it shows that the Kang Square has been contaminated, and the hatching of 2Kang should be stopped immediately. At the same time, all hatching and brooding appliances and houses should be thoroughly disinfected. It is best to use tertiary concentration of formaldehyde to fumigate 30min, and then continue to hatch. Newly hatched goslings should not come into contact with newly collected goose eggs or adult geese to prevent infection.

This article comes from the http://www.yangzhidao.com/ reprint of goose breeding net and indicates the source.