Prevention and treatment of Infectious bursal Disease in chickens

Infectious bursal disease of chicken, also known as Gampolo disease, is an acute and highly contagious disease caused by infectious bursal virus. Due to sudden onset, short course of disease, high mortality and immunosuppression of chickens, it is still one of the main infectious diseases in the chicken industry. Let's take a look at the prevention and treatment of infectious bursal disease.

Epidemic characteristics of Infectious bursal Disease in chickens

Under natural conditions, infectious bursal disease was infected only in chickens, and all breeds could be infected, but broilers of different breeds were more sensitive than laying hens, which only occurred from 2 weeks to pre-parturition, and the peak of the disease was at the age of 3-7 weeks. The virus is mainly excreted with the feces of diseased chickens, polluting feed, drinking water and the environment, so that the same group of chickens are infected through digestive tract, respiratory tract and conjunctiva. All kinds of utensils, personnel and insects can also carry the virus, spread and transmit through eggs.

Clinical symptoms of infectious bursal disease in chickens

The chicks suddenly fell ill in large numbers, affecting 60% and 70% of the chickens within 2-3 days. The death reached the peak 3-4 days after the disease, and the death stopped after 7-8 days. At the beginning of the disease, depressed spirit, reduced food intake, increased drinking water, some from pecking anus, discharge white water sample sparse feces, heavy dehydration, lying on the ground can not afford, extremely weak, and finally died. Autopsy examination showed that the bursa of Fabricius showed yellow peptone-like edema, hard, and the mucous membrane was covered with cream cellulose exudate. Sometimes the mucosa of bursa of Fabricius is severely inflamed, bleeding, necrotic and atrophied. In addition, dead chickens show dehydration, leg and chest muscles often bleed, the color is dark red. The kidney is swollen, the renal tubules and ureters are filled with white urate, and the spleen and glandular stomach and myogastric junction mucosa bleed.

Preventive measures of Infectious bursal Disease in Chicken

1. Environmental disinfection: strengthen management and do a good job in sanitary disinfection to prevent the disease from being brought into the chicken farm from the outside. once the disease occurs, disinfect the sick chickens in time and disinfect them thoroughly. Before entering the chicken house, the fumigation and disinfection pool in front of the door should use compound phenol solution, which should be changed every 2-3 weeks, or decyl methyl bromide from clean farm, once a week.

2. Vaccination: vaccination is an effective measure to prevent infectious bursal disease. At present, the vaccines approved for production in China are attenuated vaccine and inactivated vaccine, and moderately virulent live vaccine Pasteur D78 is imported.

① low virulence strain attenuated live vaccine: used for early immunization of chicks without maternal antibodies, but has poor immune effect on chickens with maternal antibodies, which can be immunized by eye, nose, intramuscular injection or drinking water.

② moderately virulent strain attenuated live vaccine: for all kinds of chickens with maternal antibodies, can be eye-tapping, oral, injection. The dose of D78 vaccine does not need to be doubled when immunized with drinking water.

③ inactivated vaccine should be matched with live infectious bursal disease vaccine when used. The immune effect is affected by immune method, immunization time, vaccine selection, maternal antibody and other factors, in which maternal antibody is a very important factor. Conditional chicken farms should formulate corresponding immune procedures according to the results of the determination of maternal antibody level.

Treatment of Infectious bursal Disease in chickens

The main results are as follows: 1. Chicken infectious bursal disease high immune serum injection: 3-7-week-old chickens, each intramuscular injection of 0.4 ml, big chicken plus dose, adult chicken injection of 0.6 ml, once injection, the effect is significant.

2. Chicken infectious bursal disease high immunity egg yolk injection: 1 ml intramuscular injection per kilogram of body weight, has a better therapeutic effect.

3. Compound alkynyl ketone: 0.5 kg chicken 1 tablet per day, 1 kg chicken 2 tablets daily, orally for 2-3 days.

4. Testosterone propionate: at the age of 3 to 7 weeks, each chicken was injected with 5 mg intramuscularly, only once.

5. Quick-acting tube capsule powder: 0.25 grams per kilogram body weight, mixed in feed or directly taken orally, effective 8 hours after taking medicine, continuous feeding for 3 days. The cure rate is high.

6. Morphine guanidine hydrochloride: 8 tablets (0.1 g each), 1 kg mixture, 15 g Banlangen granule, dissolved in drinking water. For half-day drinking, the above is 20-25 feathered chickens a day, 3 days as a course of treatment.

7. Traditional Chinese medicine treatment: 200 grams of dandelion, 200 grams of Folium Isatidis, 200 grams of Radix Isatidis, 100 grams of Shuanghua, 100 grams of Scutellaria baicalensis, 100 grams of Phellodendron Phellodendri, 100 grams of licorice, 50 grams of patchouli, 50 grams of raw gypsum. After boiling in water for 2 times, the combined juice was 3000 to 5000 milliliters, 300 to 500 feather chickens a day, one dose a day, 5 to 10 milliliters per chicken per day, 4 times for 3 days.