Prevention and treatment of Riemerella anatipestifer

Riemerella anatipestifer is a contagious disease caused by Riemerella anatipestifer (Ra), also known as duck infectious serositis, new duck disease, duck septicemia, duck plague syndrome, pasteurellosis and so on. Let's take a look at the prevention and treatment of Riemerella anatipestifer.

General prevention and treatment of Riemerella anatipestifer disease

1. It is necessary to strengthen the feeding and management, improve the feeding conditions, and feed with high-quality and full-price feed to ensure that the growth requirements can be met so as to enhance the physique of ducklings.

2. It is necessary to properly adjust the feeding density of ducks, pay attention to control the temperature and humidity in the duck shed, especially in rainy spring, hot summer and cold winter, and do a good job in keeping ducklings warm, moisturizing and ventilating, so as to minimize the effects of cold, rain, driving, sun exposure and other adverse factors.

3. Implement the feeding and management system of "all in and all out". Ducks of different batches and different ages can not be mixed together. After the ducks are out of the pen, all kinds of utensils, venues, sheds, pools and so on should be sterilized.

4. it is necessary to do a good job in site hygiene and adhere to the system of disinfection and epidemic prevention. Regularly clean and disinfect drinking fountains and troughs, and vaccinate and prevent other diseases such as duck plague, duck viral hepatitis, Muscovy duck three-week disease, Muscovy duck "flower liver" disease, bird flu and so on, so as to reduce the occurrence of other diseases. By taking these measures, the infection and occurrence of the disease can be effectively reduced.

Drug prevention and treatment of Riemerella anatipestifer disease

1. When Riemerella anatipestifer disease occurs, drug treatment can effectively control the occurrence and development of the disease. According to years of clinical experience, gentamicin, kanamycin, sulfamethoxine, cephalosporins, quinolones and other drugs have good results. Chloramphenicol has been banned in poultry farms. Florfenicol (florfenicol) can be mixed with florfenicol (florfenicol). 5% florfenicol is mixed with 0.2% of florfenicol for 5 days. Patients with severe diseases can be injected intramuscularly according to 25 mg / kg body weight for 2 days. can achieve significant results.

2. Pioneer can be injected intramuscularly with 15mg / kg body weight, or 80-10,000 units of gentamicin, combined with large groups of drugs, for 3 consecutive 5 days. Or ciprofloxacin or enrofloxacin and other 25~50ppm water-soluble free drinking, while adding a variety of vitamins, can achieve obvious therapeutic effect.

3. Because bacteria can produce resistance to antimicrobials, the effect is significant when a drug is first used in the production plant, but after using it for a while, the effect is not obvious or not. If there are conditions, we can isolate the pathogen of sick and dead ducks, test the drug sensitivity of the isolated strains, screen the cross-use of highly sensitive drugs, and use the drugs in combination with the medication history of this field.

4. The method of combination of traditional Chinese and western medicine to prevent and cure Riemerella anatipestifer can also achieve satisfactory results. For example, while injecting pioneers, fried with Huanglian, Qingmuxiang, Pulsatilla, Herba Euphorbiae, Herba Houttuyniae, mixing or filling for 3-5 days, or gentamicin for 3 days, Herba Houttuyniae, Cortex Phellodendri, Sophora flavescens, Salvia miltiorrhiza and Yinchen for 3 days, or with the Chinese herbal medicine "Anti-cystic Disease" developed by poultry in Guangdong Province, after direct dilution, drink freely for 3-5 days, at the same time add a variety of vitamins. The effect is obvious.

Immunization with Riemerella anatipestifer vaccine

Because the drug prevention and treatment is easy to cause the drug resistance of the strain, the ducks suffer from the disease repeatedly, and it is difficult to cure it once and for all. this situation is more common in the old age field, not only the drug cost is increased, the treatment effect is not good, but also when the duck comes out of the fence, the rate of rejection of the duck is also high. and vaccination with vaccines can achieve better preventive effects.

1. Riemerella anatipestifer vaccines developed abroad include univalent and multivalent inactivated vaccines, attenuated vaccines, subunit vaccines and mixed E. coli vaccines. Inactivated vaccines with various adjuvants (such as formalin inactivated vaccine, oil adjuvant inactivated vaccine, propolis adjuvant inactivated vaccine and inactivated vaccine with other adjuvants) are widely used in China, such as monovalent inactivated vaccine of type 1 Ra, 1. Type 2 bivalent inactivated vaccine, multivalent vaccine of other serotypes, bivalent inactivated vaccine of Ra and Escherichia coli, Ra and triple inactivated vaccine of Escherichia coli and Escherichia coli.

2. When ducks are immunized with inactivated vaccine, it is generally necessary to vaccinate twice in order to obtain more effective protection. Meat ducks are immunized for the first time at the age of 7-10 days, intramuscular injection or subcutaneous injection of 0.2 × 0.5 ml / duck. After 1-2 weeks of interval, the second immunization, 0.5 × 1 ml / duck, can achieve better control effect. Compared with other adjuvant vaccines and non-adjuvant vaccines, the immunity of oil-adjuvant inactivated vaccine is longer, and it is generally enough for meat ducks to be used once in the whole growing period, but oil-adjuvant inactivated vaccine often has local inflammatory reaction at the inoculation site. When vaccinated, adding an appropriate amount of multivitamins can help to reduce the stress response.

3. There are many serotypes of Riemerella anatipestifer, the main epidemic serotypes are different in different countries and regions, and the prevalent serotypes are different in different periods, and there may be multiple serotypes in the same duck farm or even in the same group of ducks. It is generally believed that there is no cross immunity among various serotypes, which brings some difficulties to the prevention and treatment of Ra vaccine. At present, it has been confirmed that there are more than 9 serotypes in China. A more effective method is to select the corresponding strains to develop a vaccine according to the main local epidemic serotypes, which can achieve a more effective control effect.

Conclusion: according to the occurrence and epidemic characteristics of the disease, the most important and fundamental way to prevent and cure the disease is to do a good job of prevention, improve the feeding management and sanitary conditions of the duck farm, minimize bad stress, and do a good job in cold prevention and warmth of ducklings. Establish a reasonable and perfect epidemic prevention and disinfection system to reduce the concurrence of other diseases, while doing a good job in management measures, reasonable vaccination should be carried out. Combined with hypersensitive drugs, comprehensive control measures can effectively prevent and control the disease, thus reducing the morbidity and death of ducks.