Control methods of Gosling Plague

Gosling plague is an acute septic infectious disease of goslings caused by Gosling plague virus. Gosling plague is characterized by mental fatigue, loss of appetite, severe dysentery, sometimes neurological symptoms and high mortality, which has a great impact on the development of the goose industry. It is urgent to do a good job in the prevention and control of Gosling plague. Let's take a look at the prevention and treatment of Gosling plague.

Gosling plague pathogen

The pathogen of Gosling plague is goose parvovirus of Parvoviridae. The virus is spherical, non-enveloped, single-stranded DNA with a size of 20-22 nm. The virus exists in the internal organs, intestines and intestinal contents of diseased goslings, and has strong resistance to acid and alkali, temperature and external environment. It is proved that the strains isolated from all over the country have the same antigenicity through the studies of serology, immunology and molecular biology. Comparing the VP3 coding stem factor sequence of the vaccine strain isolated in 1961 with that of the strain isolated in 1999, the nucleotide homology of the two strains was 96%, and the deduced amino acid homology was 98%, indicating that the vaccine prepared by the 1961 strain has long-term application value.

Gosling plague symptom

1. The most acute type: the most acute type occurs in 3-10-day-old goslings, usually without any prodromal symptoms, sudden death due to septicemia, or weakness a few hours after the occurrence of mental dullness, falling to the ground, stroking, and dying after a few struggles. the disease spreads rapidly and can spread within a few days.

2. Acute type: acute type mostly occurs in 15-day-old goslings, showing depression, loss of appetite or abstinence, loose feathers, shrinking head and neck, standing with closed eyes, being alone, unwilling to walk, moving slowly, although they can pick food with the group, but the grass is not swallowed, it is lost with picking, the nostrils of the diseased goslings are serous, around the nostrils, the diseased geese shake their heads frequently, and the amount of drinking water increases. Diarrhea gradually appeared, gray-white or gray-yellow watery dung, often rice pulp-like turbidity with air bubbles or fibrous fragments, villi around the anus were stained, beak tip and webbed color darkened (cyanosis), a few sick goslings appeared neck torsion or convulsions, paralysis and other neurological symptoms before death. According to clinical observation, most goslings occur in acute type, and the course of disease is generally 2-3 days. With the increase of age of diseased goslings, the course of disease gradually changes to subacute type.

3. Subacute type: subacute type usually occurs in the goslings at the end of the epidemic or over 20 days old, and its symptoms are mild, mainly characterized by slow movement, walking and swaying, diarrhea, reduced feed intake and slightly poor mental state. The course of the disease is usually 4-7 days, sometimes longer, and a very small number of diseased geese can heal themselves, but the goslings eat abnormally, seriously hinder their growth and development, and become "stiff geese".

Prevention of Gosling plague

1. Disinfection: the whole field is disinfected regularly (it is recommended that once a week). Spray disinfection is carried out for bedding grass, material trough and site. The dead geese should be buried deeply and treated with disinfectant powder (such as sodium trichloroisocyanurate, quicklime, etc.).

2. Introduction: good introduction and introduction of healthy geese. In order to prevent bringing back the epidemic disease, those that have been introduced should be kept in isolation for observation.

3. Immunity: geese should be immunized for the first time one month before the start of production, that is, the vaccine should be diluted 20 times with sterilized normal saline, 1 ml per goose is injected subcutaneously or intramuscularly, and the vaccine is diluted 10 times after an interval of 7-10 days. 1 ml per goose subcutaneously or intramuscularly. Make the breeder geese produce immune antibodies, and only the hatched chicks can produce immunity.

4, divide eggs: the incubation equipment, all appliances and the house and ground in Kang Square should be disinfected regularly, especially in the area where Gosling plague is prevalent. The breeding eggs of immunized and unimmunized geese should be hatched separately to avoid "bastards", so that the hatched goslings have different maternal antibodies, thus affecting the immune effect of goslings. The eggs from the epidemic area should clean up the dirt on the surface of the eggshell before hatching in the Kang, and then disinfect them and then hatch in the Kang.

Treatment of Gosling plague

1. When the disease is discovered, strict control and extinction measures shall be taken in accordance with the provisions of the Animal epidemic Prevention Law of the people's Republic of China to prevent its spread. Kill sick geese and fellow geese and bury them or burn them. Gosling in the threatened area can be injected with antiserum to prevent. Contaminated sites, appliances, etc., should be thoroughly disinfected. Gosling in the affected area is prohibited from being transferred or sold.

2. Gosling plague immune serum can also be used to prevent and cure the diseased geese. Using the fresh blood of recovered geese with Gosling plague plus 10% 2.5% sodium citrate solution, Gosling neck hypodermic injection, 1.5 × 2.5 ml / feather, re-injection 24 hours later, has a good prevention and treatment effect. If sick geese are infected with other bacterial diseases, each goose should be intramuscularly injected with 1000 / 2000 units of gentamicin, once in the morning and evening, and then treated with gentamicin for 2 days and 3 days.

3. Immunizing goslings with anti-Gosling plague serum is a key measure to prevent and cure the disease. For the goslings that came out of the shell for 1 or 2 days, 0.5 ml was injected subcutaneously each, with a protection rate of about 95%. The infected goslings were injected with 0.5 ml each, with a cure rate of 85%. When emergency prevention was made for sick chicks, 0.5 ml was injected each, and the protection rate was up to 90%. The purchased Gosling plague high immune serum should be stored in a cold and dark place of 2: 15 ℃, with a period of validity of one year. For the diseased geese who have occurred Gosling plague, you can try Violing orally, 1 tablet once or twice a day, which will have a certain curative effect.