Efficacy and function of Pinellia ternata

Pinellia ternata, also known as Pinellia ternata, Panax notoginseng and mad dog potato, is the tuber at the tip of the plough tip of the Araceae plant. In autumn and winter, the tuber is dug to remove the skin and fibrous roots and then dried in the sun. It has the effects of dryness, dampness, detoxification, detumescence and hemostasis. It has therapeutic effects on coughing phlegm, carbuncle, boil, nameless swelling, poisonous insect stings, traumatic bleeding and so on. Let's take a look at the efficacy and effect of Pinellia ternata.

Medicinal effect of Pinellia ternata

The taste is pungent, warm and poisonous.

Meridian of lung and spleen.

[efficacy] dryness and dampness, detoxification and detumescence, hemostasis, cough with more sputum, carbuncle, boil, nameless swelling, insect stings, traumatic bleeding.

[usage] for internal use: fried soup, 3-9 grams, or into pills, powder. External use: mash compress, or research final adjustment compress.

[taboo] toxic, Yin deficiency dryness cough and pregnant women use with caution.

Pharmacological effects of Pinellia ternata

1. Antiemetic effect: 50 g / kg decoction of Pinellia ternata can significantly reduce the number of vomiting induced by copper sulfate in pigeons, with a reduction rate of 50%, but can not reduce the number of vomiting only. Its antiemetic effect and intensity are similar to those of Pinellia ternata. The effect of processed products was weak, and the vomiting reduction rates of the old method and the new method (directly soaked in saturated alum water) were 28.7% and 11.8%, respectively.

2. Antitussive effect: 25% suspension of raw Pinellia ternata and old and new products were given to mice with 10 g / kg, which had obvious antitussive effect on cough caused by concentrated ammonia water. the antitussive rate of the new method was 44.8%. The raw and old products were 25.5% and 20.4%, respectively.

3. Expectorant effect: determined by mouse phenol red method, the raw product of Pinellia ternata and the alcohol extract of the new and old method products were infused with 300g / kg, and the new and old method products had certain expectorant effect, and the intensity of the effect was 225% and 173% of that of the control group, respectively, while the raw product had no obvious expectorant effect. The expectorant effect of Pinellia ternata is slightly stronger than that of Pinellia ternata.

4. Antiarrhythmic effect: the decoction of Pinellia ternata was given to rats by intragastric administration of 53g / kg, which had an antagonistic effect on ventricular arrhythmias induced by barium chloride. the duration of ventricular extrasystole in distilled water group was changed from 81.54 ±15.73min to 24.87 ±5.73min.

5. Central inhibition: intraperitoneal injection of 60 g / kg of Pinellia ternata decoction had a significant inhibitory effect on the spontaneous activity of mice, but the effect of 30 g / kg group was not obvious. High dose slightly increased the sleep time of pentobarbital sodium and antagonized electroconvulsion, but the difference was not statistically significant. The armature inhibition was weaker than that of Pinellia ternata.

6. inhibitory effect of Pinellia ternata decoction on saliva secretion: intragastric administration of 60 g / kg Pinellia ternata decoction could not only inhibit the saliva secretion caused by pilocarpine, but also reduce the phenomenon of tears and the degree of pupil contraction. It is speculated that the effect of atropine may be similar to that of atropine, which may be related to its effect of "dryness and dampness", which can also explain the clinical manifestation of dry mouth.

7. Other effects: the alcohol extract of Pinellia ternata has antioxidant effect, and the inhibition rate of IR (%) on the automatic oxidation of linoleic acid is 94.1%. The suspension of Pinellia ternata can induce vomiting by intragastric administration of domestic pigeons, and the half effective dose of vomiting is 1.22 g / kg. When the dosage of crude medicine decoction was 100 g / kg, 60% of domestic pigeons had diarrhea. The new and old cannon products had no obvious emetic effect.

The difference between Pinellia ternata and Pinellia ternata

1. The original plant of Pinellia ternata is the dry tuber of Pinellia ternata of Araceae. The original plant of Pinellia ternata is a dry tuber with a whip eave tip of the plough tip of Araceae.

2. The contents of β-sitosterol, amino acid, oleic acid and inorganic elements in Pinellia ternata and Pinellia ternata are completely different.

3. The toxicity of Pinellia ternata is different from that of Pinellia ternata. The toxicity of Pinellia ternata is 3.2 times that of Pinellia ternata.

4. The antitussive and antiemetic effect of Pinellia ternata was stronger than that of Pinellia ternata, and Pinellia ternata had no antiemetic effect.