Efficacy and function of Tripterygium wilfordii

Qingfeng rattan is also known as wind-seeking vine, Qingfeng vine, Dianfangji, etc., in order to prevent the dry rattan stems of plants that already belong to Qingfeng vine, medicine has the effect of dispelling rheumatism, dredging channels and collaterals, and promoting urination. It has therapeutic effects on rheumatism arthralgia, joint swelling, paralysis and pruritus, and should not be confused with Qingfeng rattan. Let's take a look at the efficacy and effect of Qingfeng rattan.

Medicinal effect of Tripterygium wilfordii

The taste is bitter, pungent and flat.

Meridian of liver and spleen.

[efficacy] remove rheumatism, clear channels and collaterals, relieve urination, mainly treat rheumatism arthralgia, joint swelling, paralysis and itching.

The discussion of Qingfengteng

1, "Materia Medica Huiyan": Qingfeng rattan, scattered wind-cold-dampness arthralgia medicine, can relax muscles and promote blood circulation, bone and marrow, so the wind disease is weak, and strong partial waste syndrome, long-term service often take, build Qigong. It must be used with Angelica sinensis and Chinese wolfberry.

2. "Materia Medica will be read": all the vines can pass through the meridians and enter the collaterals, and this thing is good at treating wind diseases, so all the paralysis in the calendar is cured, and it is especially good to soak wine. The wind passes through the liver, so it enters the liver, the wind wins the dampness, and the dampness passes through the spleen.

Medicinal prescription of Tripterygium wilfordii

1, cure rheumatism arthralgia: green rattan root two or two, prevent oneself one or two, into a bottle of wine, boil drink; green wind rattan, red vine each 15 grams, water frying, add the right amount of wine to take.

2, treat bone joint wind pain: big green wood Gyabgon or stem and leaf appropriate amount, decoct water often wash sore place.

3. Cure all kinds of wind: pick it in March or second, no matter how much it is, go into the cauldron, stay up for seven days and nights, make the ointment and put it into the porcelain bottle. When using it, first prepare three or five combs, measure the deficiency and reality of the person, finish with a teaspoon of wine, pat the patient's body, and then itch all over the body. Hurry to comb it. If you want to stop the itch, you can drink cold water and relieve it. Take shelter from the wind for several days.

Pharmacological effects of Tripterygium wilfordii

1. Antihypertensive effect: the antihypertensive effect of total alkaloids of Tripterygium wilfordii is rapid and powerful, and it is not easy to produce rapid tolerance after repeated administration. No matter what kind of administration route is used, it has a definite acute antihypertensive effect on anesthetized or unanesthetized animals. However, sinomenine is easy to be rapidly tolerated after repeated use.

2. Anti-inflammatory effect: sinomenine tablets can significantly inhibit adjuvant arthritis in rats, inhibit carrageenan-induced paw swelling and Agar granuloma formation in rats, antagonize the increase of vascular permeability induced by 5-HT, and significantly inhibit writhing induced by acetic acid in mice.

3. Analgesic effect: mouse hot plate method, electric stimulation method and rabbit photothermal stimulation method all proved that sinomenine had significant analgesic effect, its intensity was about l/2.5~1/l0 of morphine, its duration was short, continuous use could also produce tolerance, but it was slower than morphine, and the drug resistance disappeared after a few days of withdrawal.

4. Sedative effect: sinomenine significantly reduced the spontaneous and passive activity of mice, had no significant effect on barbiturate sleep time, and had some antagonistic effect on strychnine (lowering the convulsion threshold of strychnine on mice). But it can't resist pentamethene tetrazole. Oral sinomenine 45 mg / kg in dogs and monkeys also had a significant sedative effect.

5. Antitussive effect: sinomenine has antitussive effect on mice (S02 method) and cats (electrical stimulation of superior laryngeal nerve). Its antitussive effect is similar to that of codeine in guinea pigs (S02 method). Promethazine can enhance its antitussive effect.

6. Other effects: Qingfengteng can inhibit the contraction of isolated rabbit intestinal smooth muscle and antagonize the intestinal contraction induced by Ach, histamine and pilocarpine. Methanol extract can enhance the contractility and muscle tension of uterine smooth muscle of pregnant, non-pregnant and postpartum rabbits. With the increase of dose, semi-spasmodic contraction occurred in turn, until tetanic contraction appeared. Qingfeng vine has a certain cooling effect and weak emetic effect.