Effects and Functions of Semen Strychni

Nux vomica, also known as strychnine tree, soft-shelled turtle, bitter beans and so on, are the dry and mature seeds of Strychnos nux vomica. It has the effect of dredging collaterals and relieving pain, dispersing knots and detumescence, and has therapeutic effects on injuries, fractures, rheumatism, numbness, paralysis, carbuncle, sore throat and other diseases. let's take a look at the efficacy and effect of nux vomica.

The Medicinal value of semen Strychni

[taste] bitter taste, warm nature.

Meridian of liver and spleen.

[efficacy] dredging collaterals and relieving pain, dispersing knots and detumescence, mainly treating injury caused by fall, swelling and pain of fracture, stubborn arthralgia of rheumatism, numbness and paralysis, carbuncle, sore throat.

Pharmacological effects of semen Strychni

1. The effect on the central nervous system: strychnine contained in nux vomica has an exciting effect on the whole central nervous system, and can improve the function of the sensory center of the cerebral cortex, mainly acting on the spinal cord and stimulating its reflex function. make nerve impulses easy to transmit between neurons. It also has the function of stimulating the brain, causing sensitivity to the functions of various sensory organs, awakening patients in a state of inhibition, and regulating the excitement and inhibition process of the cerebral cortex.

2. Analgesic effect: brucine has significant analgesic effect. Acetic acid writhing test in mice showed that its analgesic effect was weaker than that of pethidine, but its duration was about 4 times longer. the hot plate method in mice also showed that brucine had obvious analgesic effect in a certain dose and time limit, while strychnine had no obvious analgesic effect.

3. Effect on digestive system: the direct test of intestinal fistula showed that strychnine had no excitatory effect on human gastrointestinal smooth muscle, but because of its strong bitter taste, it could stimulate the reflex of taste receptor to increase gastric juice secretion. therefore, it can promote digestive function and increase appetite. Animal experiments also show that an appropriate amount of nux vomica powder can excite the rumen and treat pre-gastric relaxation. On the other hand, excessive dosage will inhibit rumen peristalsis and aggravate forestomach relaxation.

4. The effect of brucine on respiratory system: the effect of brucine is strychnine. It is reported that brucine has a strong antitussive effect on cough in mice induced by ammonia and sulfur dioxide, and its intensity is higher than that of codeine, and the effect of oral administration is more significant than that of intraperitoneal injection. Phenol red excretion method in mice shows that brucine 40mg/kg has obvious expectorant effect, and its intensity is not significantly different from that of ammonium chloride, but its antiasthmatic effect is weak.

5. Effect on pathogenic microorganisms: nux vomica decoction (1:2) had different inhibitory effects on Xanthophytes xylanense, Microsporum auduum and other skin fungi in the test tube. In vitro experiments showed that 0.1% brucine could completely inhibit the growth of Haemophilus influenzae, Diplococcus pneumoniae, Alpha streptococcus and catarrhal cocci.

6. other effects: high concentration of nux vomica decoction can inhibit the mitosis of lymphocytes, while low concentration can promote the mitosis of cells. Brucine has a paralytic effect on sensory nerve endings. 5-10% brucine solution can anesthetize oral mucosa. On isolated muscle nerve specimens, large doses of brucine and strychnine can block neuromuscular conduction and show arrow-like effect. In whole animals, this effect is masked by systemic convulsion.

The medicinal effect of nux vomica

1. Fall injury: Ma Qian Zi is good at dispersing knots, reducing swelling and relieving pain. it is a good product for trauma treatment and pain relief. Treatment of injury, fracture swelling and pain, can be equipped with ephedra, frankincense, myrrh, and so on into pills, such as nine scattered. It can also be used in the same way as pangolins, such as Ma Qian San and Qinglong pills.

2. Carbuncle and gangrene: nux vomica is poisonous and can disperse knots and detumescence, attack poison and relieve pain. For the treatment of carbuncle and gangrene, it is often used for external use, and it is effective if used alone. To treat throat arthralgia and pain, it can be divided into green wood incense, soya bean root and so on, such as Punmu Turtle Powder.

3. Rheumatism stubborn arthralgia: nux vomica can search rheumatism between muscles and bones, open channels and collaterals, penetrate joints, and relieve pain. it is a common medicine for treating rheumatic stubborn arthralgia, clonic pain, numbness and paralysis. it is effective alone, and it can also be taken with ephedra, frankincense, scorpion and so on. Or with licorice, such as "Modern practical traditional Chinese Medicine" with this product and licorice as the end, honey for pill service, to treat hand and foot numbness, hemiplegia.

4. Dissipating heat and eliminating blood stasis: nux vomica is bitter, cold and poisonous. Bitter to release closure, rattan nature of good deeds scattered, cold can clear heat. Enter the two meridians of the liver and spleen, with the function of dispelling heat and eliminating blood stasis, suitable for carbuncle, swelling and pain. Most of them are caused by exogenous six masturbation, thick taste of plaster and sorghum, internal depression of dampness, heat and fire poison, or external injury, feeling of poison, etc., resulting in the accumulation of evil poison, resulting in discord between Ying and Wei, obstruction of meridians and collaterals, and stagnation of qi and blood.

5. Detumescence and pharynx: nux vomica has the effect of relieving swelling and relieving pain. For throat pain, due to accumulation of evil toxin, qi stagnation and blood stasis, meridian blockage, characterized by redness, swelling and pain in the pharynx, or slightly red throat itching, the treatment of nux vomica. Such as "Medical prescription Abstract" said to treat throat pain, with it compatible with soya bean root, green wood research end blow throat.

6. To eliminate pain and dissolve ruffians: "Danxi Heart method" says that qi cannot be grouped together. Blocks are tangible things, which are formed by phlegm and food accumulation and dead blood. " Abdominal ruffian, mostly in the epigastric or umbilical abdomen, epigastric distension full of pain, pain refused to press, eating less, thin body tired, pale complexion, light tongue and fine pulse. Treat nux vomica to dispel blood stasis and eliminate dyspnea and dispel ruffian. For example, "Materia Medica from the new" said: "Ma Qian Zi, eliminate riffraff blocks."

7. Heat-clearing and detoxification: nux vomica tastes bitter and cold. Bitter release of fire, cold can be better than heat. Clearing away heat and detoxification, searching for wind and relieving pain. It is used for the syndrome of fear of water and evil wind, strong heat and clonus caused by mad dog bite. For example, the secret recipe of traditional Chinese medicine is to treat rabies, a nux vomica, wine ground into powder, boiled water to swallow.