Symptoms and treatment of Haemophilus parasuis in pigs

Porcine Haemophilus parasositis, also known as multiple fibrinous serositis and arthritis, Glazer's disease, etc., is caused by Haemophilus parahaemophilus, which is ubiquitous in the environment. For pigs that do not have specific pathogens or get up early and are not contaminated by Haemophilus parasuis, the consequences will be quite serious when they are first infected with this bacteria. Let's take a look at the symptoms and treatment of Haemophilus parasuis.

Develop symptoms

Haemophilus parasuis only infects pigs and can affect young pigs from 2 weeks to 4 months of age, mainly before and after weaning and during the conservation stage. It is commonly seen in 5-8-week-old pigs, with an incidence of 10-15% and a mortality rate of 50% in severe cases. Acute cases often occur first in pigs with good body condition, with fever (40.5-42.0 ℃), depression, loss of appetite, dyspnea, abdominal breathing, redness or pallor of the skin, purple ends of the ears, subcutaneous edema of the eyelids, slow walking or reluctance to stand, enlargement of the wrist and tarsal joints, ataxia, lying on the side or watery limbs before death, and sometimes sudden death without obvious symptoms. Chronic cases are more common in nursing pigs, mainly loss of appetite, cough, dyspnea, rough coat, weakness or claudication of limbs, poor growth, until brown and death.

Ways of transmission

Haemophilus parasuis spreads through the respiratory system, and it is more likely to occur when there is reproductive respiratory syndrome, influenza or endemic pneumonia in pigs, and it is more likely to occur in poor environment and water cut-off conditions. Weaning, herding, mixing or transportation are also common causes. Haemophilus parasuis is also a secondary pathogen accompanied by mixed infection of other major pathogens, especially endemic porcine pneumonia. In pneumonia, Haemophilus suis is assumed to be a secondary pathogen of random invasion, a typical "opportunistic" pathogen that causes disease only in conjunction with other viruses or bacteria.

Precautionary measures

1. Strict disinfection: thoroughly clean the pig house, spray the pigsty floor and wall with 2% sodium hydroxide solution, rinse it with clean water after 2 hours, then disinfect it with Kexing compound iodine spray and disinfect it continuously for 4 days.

2. Strengthen the management: the whole herd of pigs should drink water with electrolyte and vitamin C powder for 5 days to enhance the body resistance and reduce the stress reaction.

Treatment method

1. Severe injection: intramuscular injection, 0.2 ml / kg each time, once every morning for 5-7 days.

2. Kanamycin sulfate injection: intramuscular injection, 20 mg / kg each time, once a night for 5-7 days.

3. Oxytetracycline pure powder: large groups of pigs take oxytetracycline pure powder 30 mg / kg, once a day for 5-7 days.

4. Antibiotics: antibiotic drinking water may not be effective for serious outbreaks of the disease. once clinical symptoms appear, antibiotics should be used to treat the whole herd immediately, and high-dose antibiotics should be injected intramuscularly in sick pigs.

5. Cellulose-lytic enzyme: oral cellulose-lysing enzyme (Lick) can quickly remove cellulosic exudates, relieve symptoms and control pig mortality while being treated with antibiotics.