Ciliary abnormalities in bronchiectasis

Infection, hereditary and congenital, abnormal cilia and so on can lead to bronchiectasis. Among them, abnormal cilia cause bronchiectasis, which may be more difficult for people to understand and understand. Share here. Cilia are found in the nasal cavity, trachea, bronchi, and even the esophagus, intestines and many other internal cavities. However, after the occurrence of cilia abnormality, it shows different phenomena and results because of its different location and function.

The occurrence of abnormal cilia actually refers to the abnormal structure and function of cilia, resulting in poor cilia movement, greatly reduced clearance function, or even complete loss. From the initial appearance of abnormal cilia, to a more severe state, there will be sinusitis, bronchiectasis, visceral transposition and other "triad" disease.

Sinusitis and other conditions in the "triad" will show recurrent attacks, and abnormal cilia can easily cause bronchitis, pneumonia, otitis media, ectopic pregnancy, infertility and hydrocephalus. In modern pathological analysis, after the appearance of abnormal cilia, there will be some phenomena, such as loss of radiation amplitude, complete disappearance of ciliary dynamic protein arm, loss of central microtubule, abnormal number of surrounding microtubules and so on.

In terms of physical signs, after abnormal cilia, there may be signs such as barrel chest, thick breathing sound in both lungs, widening of intercostal space, scattered wheezing and other signs; abnormal texture structure of pulmonary striae, emphysema and diffuse lesions in both lung fields can be seen in CT examination; trachea mucosa congestion and more yellow mucous sputum may be found in tracheoscopy.