How to identify Streptococcus suis infection? What are the methods of prevention and treatment?

Streptococcus suis is a kind of gram-positive cocci with capsule, and some strains can cause human infection. So how do you identify it? What are the methods of prevention and treatment? It is understood that the disease can be divided into three types: porcine septicemic streptococcosis (septic type), porcine streptococcal meningitis (meningitis type), and porcine lymph node abscess (lymph node abscess type).

I. three types of Streptococcus suis infection

1. Septicemia can be divided into the most acute, acute and chronic. Among them, the most acute cases are mainly seen in the early stage of the epidemic, the disease is urgent, the course of disease is short, and pigs often die suddenly without any abnormal symptoms. The acute type pigs showed mental depression, body temperature rising to 430C, missed fever, loss of appetite, flushing of conjunctiva, tears, serous or purulent secretions from nasal cavity, shortness of breath, cough occasionally, purplish red skin in neck, auricle, abdomen and lower extremities, bleeding spots, claudication, longer course of disease, and died within 1 week or 3 days. Most of the chronic cases changed from acute to acute, and most of the diseased pigs showed polyarthritis, such as joint swelling, pain, high claudication, even unable to stand, severe paralysis, and the course of disease could reach 2-3 weeks.

two。 Meningitis is the main symptom of meningitis. Mostly occurred in suckling and weaned piglets, mainly manifested as neurological symptoms, such as motor disorders, blind walking, turning, empty chewing, molars, supine, hindquarters paralysis, lying on the side on the ground, swimming limbs. The short course of the disease is a few hours, and the long one to five days, the fatality rate is extremely high. The long course of disease is characterized by polyarthritis.

3. Lymph node abscess type is caused by Streptococcus suis infection through mouth, nose and skin, and is more common in weaned piglets and fattening pigs. The main manifestations are suppuration and abscess of lymph nodes in submandible, pharynx, ear, neck and so on. The course of disease ranged from 3 to 5 weeks.

2. prevention and treatment of Streptococcus suis infection

1. Do a good job of disinfection, elimination of the source of infection, isolation treatment of pigs, infected sows as far as possible elimination. The contaminated utensils and environment are thoroughly disinfected with 3% disinfectant such as laisuer solution. The carcass of pigs slaughtered or found suspicious pathological changes after slaughtering can only be eaten after high temperature treatment.

two。 Maintain environmental hygiene and eliminate infection factors often clean the inside and outside of the pigsty to prevent sharp objects on the pigsty and feed trough from stabbing pigs. Newborn piglets should be aseptically ligated and disinfected with iodine tincture immediately.

3. Due to the large number of serotypes of Streptococcus suis, different vaccines have no cross protection or little cross protection against different serotypes of Streptococcus suis. It is best to choose the same serotype vaccine for prevention. It is best to use attenuated live vaccine because cellular immunity plays an important role in preventing Streptococcus suis infection.

4. After the occurrence of the disease in or around the pig farm, if the vaccine is not available temporarily, the drug can be added to the feed for prevention to control the occurrence of the disease.

5. Personnel protect people from Streptococcus suis infection mainly through contact with dead pigs. Pig breeders and slaughtering and processing personnel are susceptible to the disease. In the process of pig breeding, breeders should pay more attention to personal protection, try to avoid contact with sick pigs when there is trauma, and inform veterinarians for diagnosis and treatment in time when diseased pigs are found. Slaughtering and processing personnel should prevent personal injuries when slaughtering live pigs. Once injured, the wound should be treated immediately. After cleaning and disinfection, antibiotics should be used for preventive treatment. Pay attention to do not eat sick and dead pigs, the purchase of pork in segmentation, should use raw and cooked separate board, and fully cooked after consumption.

III. Treatment of Streptococcus suis infection

Treatment plan 1: Gao re Tong Zhi + Dexamethasone Sodium Phosphate injection: Gao re Tong Zhi 0.05-0.2ml/kg, Dexamethasone Sodium Phosphate injection 10-15ml/ times, mixed intramuscular injection, twice a day for 4 days. Description: the selection of antimicrobial agents is sensitive to streptococci and mainly inhibits peptide chain affecting protein synthesis to achieve antibacterial effect. Dexamethasone has strong anti-inflammatory effect, and the combination of dexamethasone and dexamethasone has a good effect on bacterial infection.

Treatment plan 2: compound sulfadiazine sodium injection + Banlangen injection: compound sulfadiazine sodium injection 20-40ml/ times, Banlangen injection 10-20ml/ times, mixed intramuscular injection, twice a day for 3-5 days. It shows that sulfonamides belong to broad-spectrum bacteriostatic agents, which are effective against streptococci of Gram-positive bacteria, and can block the synthesis of folic acid of bacteria, thus achieving bacteriostatic effect. Radix Isatidis has the effect of heat-clearing and detoxification, and the combination of the two can clear heat and detoxify and achieve the therapeutic effect.

Treatment plan 3: Quandi + Gao re Tongzhi + Dexamethasone Sodium Phosphate injection: Quandi 20-40ml/ times, High Heat Tongzhi 0.05-0.2ml/kg, Dexamethasone Sodium Phosphate 5ml/ times, mixed intramuscular injection, twice a day for 3-5 days. It shows that sulfonamides can enter the brain through the blood-brain barrier and have bacteriostatic effect; hyperpyretic Tongzhi has antibacterial effect on a small number of streptococci, dexamethasone has strong anti-inflammatory effect, antibacterial and anti-inflammatory effect, and has a good effect on bacterial infection.