Application method of Newcastle Disease Vaccine

According to the inquiry of the sick chickens admitted to the hospital, most of them were found to be infected because the householder did not immunize according to the regular immunization procedure. In order to facilitate the majority of chicken households, the correct use of Newcastle disease vaccine was introduced.

Newcastle disease immunization is an important measure to prevent and control Newcastle disease. Live vaccine and inactivated vaccine are the main vaccines used for Newcastle disease immunization in clinic. Whether live vaccine or inactivated vaccine, there are many factors affecting the immune effect of Newcastle disease. In practice, sufficient attention should be paid to the selection of vaccine types, the formulation of epidemic prevention procedures, vaccination routes and operation methods, so as to minimize immune failure or adverse reactions.

The age of first immunization of Newcastle disease vaccine is 7~ 9 days. If the age is too young and the maternal antibody titer is high, the immunization can not stimulate the immune response, but the antibody will be neutralized, resulting in immune failure. Too late, easy to appear immune blank period, antibody titer lower than the critical protection value, resulting in the occurrence of Newcastle disease, epidemic. It is best to determine the age of first immunization by laboratory testing of maternal antibody levels to Newcastle disease.

1. Drip immunization method

Drip immunization method refers to nasal drops, eye points, through the upper respiratory tract or conjunctiva for immunization a method. Dilute 500 doses of vaccine with 25ml diluent, lift the chicken head and neck horizontally, block one nostril with hand, and then drop one drop of vaccine into eyes and nose respectively. After inhalation and diffusion of vaccine in eyes, gently put chicken back. Be careful of details such as leakage, heavy drop or non-inhalation.

2. Drinking water immunization method

In order to avoid the influence of pollutants or organic substances on Newcastle disease virus in vaccine, clean drinking water system first, then mix vaccine with about 30% of daily drinking water of chickens, and quickly fill drinking water container with vaccine-containing water, so as to avoid insufficient drinking water or uneven drinking amount of vaccine for chickens. Xiao Longnu 18845079758 vaccine drinking time is best at feeding, because the chicken group when drinking water rate is much higher than usual, at this time the vaccine can better contact with the chicken mucosa. According to the weather conditions or chicken house temperature, the water supply for chickens shall be stopped for 2~4h, so as to ensure that the vaccine shall be drunk within 2h.

3. Aerosol immunization method

It refers to using compressed air to form atomized particles with a diameter of 1~10μm through an aerosol generator, which are uniformly suspended in the air and enter the chicken body with respiration. Fog particle size should be moderate, fog particle too large, stay in the air for a short time, but also easy to be blocked by mucous membranes, can not enter the respiratory tract; fog particle too small, easy to be exhaled. In addition, the chicken house should be closed during aerosol immunization, reduce air flow, and open the doors and windows 20 minutes after spraying.

4. Injection immunization method

Newcastle disease| Line vaccine and oil emulsion vaccine are used by injection immunization method, especially oil emulsion inactivated vaccine has the advantage of high antibody level and long maintenance time, and is widely used in clinic. In practice, the problems caused by improper injection of inactivated vaccine are also various and should be paid great attention to. Chickens were injected subcutaneously into the neck.