Is the latest version poisonous?

Platycodon grandiflorum can be eaten as vegetables, but also as medicine, is a perennial herb, roots can be used as medicine, cough expectorant, Xuan lung, discharge pus and other effects, most of China are produced, and orange or citrus has no direct relationship, let's take a look at Platycodon grandiflorum poisonous bar!

Is Platycodon grandiflorum poisonous?

Platycodon grandiflorum is nontoxic. Platycodon grandiflorum can stimulate gastric mucosa after taking, too large a dose, can cause mild nausea, even vomiting, gastric and duodenal ulcer with caution, the dose should not be too large.

Toxicity Test of Platycodon grandiflorum

Platycodin has hemolytic effect, can not be used for injection, oral hydrolysis in the digestive tract after destruction, that is, no hemolytic effect. The LD50 of Platycodon grandiflorum decoction was 24g/kg in mice and 40g/kg in rabbits. All 5 rabbits died within 24 hours. All rabbits survived at the dose of 20g/kg.

The hemolytic index of platycodon grandiflorum varied from 1:100 to 1:1000, and the hemolytic effect of phloem was 4.4~6.5 times of that of parenchyma. The hemolytic effect of platycodon grandiflorum without peeling was slightly greater than that of platycodon grandiflorum without peeling. Therefore, Platycodon grandiflorum should not be injected. The minimum lethal dose of subcutaneous injection in mice is 770 mg/kg. The median lethal dose of crude platycodon grandiflorum in mice and rats by gavage is 420 mg/kg and 800 mg/kg, respectively, and subcutaneous injection is 22.3 mg/kg and 14.1 mg/kg, respectively. Large doses of platycodon grandiflorum by gastric perfusion can stimulate vomiting center reflexively, and can cause nausea and vomiting.

The efficacy and function of Platycodon grandiflorum

[Nature] bitter, spicy, flat.

[Channel Return] Lung Channel.

[Efficacy] Xuan lung, expectorant, sore throat, pus discharge, qi regulation, blood circulation, digestion, calm the mind.

1. Cough and phlegm, chest distress: Platycodon grandiflorum is bitter and diarrhea, opens lung qi, eliminates phlegm, and can be applied regardless of cold and heat. Cold, with perilla, almond, such as apricot Su San ("warm disease article differentiation"). Wind-heat, with mulberry leaves, chrysanthemum, almond, such as mulberry and chrysanthemum drink ("warm disease differentiation"). If the treatment of phlegm stagnation chest mass, often with bitter orange used.

2, sore throat, aphonia: platycodon grandiflorum can Xuan lung discharge evil to benefit throat opening sound. For those with exogenous pathogens invading the lungs, sore throat and aphonia, it is often used with licorice root and burdock fruit, such as platycodon grandiflorum decoction (Synopsis of Golden Chamber) and modified ganju decoction (Medical Heart Enlightenment). Treatment of sore throat, heat and toxin Sheng, can be matched with Belamcanda chinensis, Pubo, Isatis root and so on to clear away heat and detoxify throat.

3, lung carbuncle vomiting pus: platycodon grandiflorum scattered upward, can benefit lung qi to discharge lung pus phlegm. Cure lung carbuncle cough chest pain. Phlegm stink, can be used with licorice, such as platycodon grandiflorum soup ("Golden Chamber Synopsis"). Clinically, it can be combined with Houttuynia cordata and wax gourd kernel to strengthen the effect of clearing lung and discharging pus.

4. Platycodon grandiflorum has antitussive effect, enhances anti-inflammatory and immune effect, and its anti-inflammatory intensity is similar to aspirin. Water extract can enhance phagocytic function of macrophage, bactericidal ability of neutrophils and lysozyme activity. It has preventive effect on stress ulcer.

5. Platycodon grandiflorum crude saponin has sedative, analgesic and antipyretic effects, and can lower blood sugar, cholesterol and relax smooth muscle. Platycodon grandiflorum has a strong hemolytic effect, but oral administration can be broken down in the digestive tract and lose hemolytic effect.