Treatment of Pseudomonas aeruginosa in cultured ostrich

Pseudomonas aeruginosa is widely found in air, feces, soil and sewage ponds. It is a gram-negative bacilli with flagella at one end and motility. The bacteria grew well on the common medium, produced blue-green pigment and aromatic smell, and formed a hemolytic circle on blood Agar. The strain can produce exotoxin and can easily form drug-resistant strains. The disease can occur in ostriches of all ages, and chicks aged from 1 to 90 days old are more likely to be infected, most of them die of septicemia, and the fatality rate is very high. Contaminated sites, water sources, soil, forage and air are important sources of epidemic, and there are various ways of transmission.

Depressed spirit and even malaise, loss of appetite and even abstinence, unwilling to exercise, body temperature rose to more than 42 ℃. Discharge green or yellow-white loose stool, anal pollution, edema. Tears, eyelid edema, purulent secretions around the eyes, corneal ulcers in some eyes, severe blindness, and most of them died. There are bleeding changes in parenchyma organs, including bleeding spots and spots in heart, spleen, liver, brain and kidney, stomach and intestine. The liver was yellowish and swollen with small yellowish-white necrotic foci scattered.

Prevention and control measures:

1. Treatment: 3 000 ~ 5 000 units / kg body weight of gentamicin can be injected into the muscle of diseased birds, and erythromycin eye ointment is used to treat ophthalmopathy, daub twice a day.

2. Prevention: the key point is to do a good job of environmental hygiene and carry out regular and thorough disinfection, especially for hatchery, incubator, nursery and bedding.

As for immune prevention, it is generally believed that the inactivated formaldehyde vaccine prepared by strains isolated from this area (field, group) containing multiple serotypes can produce immunity 5-6 days after vaccination, and the immune period is about half a year.