How to prevent and cure tuberculosis in cultured nutria

Tuberculosis (Tubercu). Sis) is a chronic infectious disease of livestock, poultry, fur animals and human beings, which is endemic. Tuberculosis is characterized by the formation of caseous and calcified tuberculosis nodules in the internal organs. The pathogen of tuberculosis is Mycobacterium tuberculosis. This bacteria is a neat straight or slightly curved pleomorphic bacilli, 1.5 microns long and o.2-0.5 microns wide, scattered or clustered individually, neither forming a capsule nor spores, nor motility, and acid-resistant dyeing. It is not easy to dye aniline dye, but it can be dyed red by adding carbolic acid as a mordant in compound red. After coloring, acid can not make it fade. Mycobacterium tuberculosis is an exclusive aerobic bacteria, its growth is relatively slow in the culture medium, the medium is suitable for the growth of Mycobacterium tuberculosis by adding appropriate amount of glycerol, whole egg, egg yolk or protein and animal serum. Tuberculosis has strong resistance to dry environment and is sensitive to sunlight and damp heat. It kills after several minutes to several hours in direct sunlight. 5% of Lysol was killed in 48 hours and died quickly in 10% bleach. This strain is not sensitive to sulfonamides and general antibiotics, but has different degrees of sensitivity to streptomycin, isoniazid and aminosalicylic acid. (epidemiology) the occurrence of the disease is not seasonal, it can occur in all four seasons, and it is more common in summer and autumn. Narrow enclosure, intensive feeding, fecal accumulation, malnutrition, helminthiasis and colds can promote the occurrence and prevalence of the disease. The young mice are easy to suffer from the disease, but the adult and healthy mice are not easy to get sick, and the mortality is relatively low. (the clinical symptoms make most of the cases show failure, dishevelled and dull. When lung lesions occur, the main symptoms are cough, respiratory frequency and dyspnea, inactivity and so on. Tuberculosis cases of liver, kidney and other parenchymal organs often have no clinical symptoms, while some sick rats have diarrhea or constipation and hydrops in the abdominal cavity. Lymph nodes are invaded by Mycobacterium tuberculosis and often appear ulcers or nodules that do not heal for a long time.

Diagnosis: tuberculosis in nutria often lacks characteristic clinical symptoms, so clinical diagnosis is difficult and can only be diagnosed by pathological anatomy and bacteriological examination. Pathological and anatomical changes: specific caseinated or calcified tuberculosis nodules of different sizes occurred in the diseased organs. Bacteriological examination method: the disease material was stored in 409 "sterilized glycerol, made into smear, stained according to Ziehl-Neelsen staining method, and red acid-fast Mycobacterium tuberculosis was found on the green background before diagnosis could be made. Prevention and treatment measures: nutria that are positive and suspicious to tuberculin should be kept in isolation until the skin is removed. The enclosure where the sick rats lived was disinfected with flame blowtorch or 291.6 caustic soda solution, and the ground was sprayed with bleach. It is not easy to cure the disease, and the course of treatment is long, so those who have no medical value should be eliminated instead of treatment, so as to avoid the spread of the epidemic.