How much is the traditional Chinese medicine motherwort seed per jin?

Motherwort, also known as Yi, Wei, Kuncao, Jiuzhonglou, Mica, Sendi and so on. It is a famous traditional Chinese medicine, and the whole herb can be used as medicine. So how much is a jin of motherwort seeds? What is the evidence of toxic components and toxicity of motherwort and the evidence quality and future research plan of motherwort injection? Let's get to know it.

1. How much is the seed of motherwort per jin

The market price of motherwort seeds has been very stable, the price per jin of seeds is about 75 yuan to 90 yuan, this price is still very low, or within the acceptable range.

2. research evidence on toxic components and toxicity of motherwort

At present, there are few studies on the toxicity of motherwort, especially the toxic and side effects of proprietary Chinese medicine preparations of motherwort, suggesting that the material basis, mechanism and characteristics of toxicity of motherwort and its preparations should be further studied. to study the dose-response relationship between dose and toxicity, and to explore the methods of reducing toxicity in clinical use of motherwort. To provide evidence basis for the establishment of safety limits for the use of motherwort and its preparations, and to provide reference for its clinical reasonable and safe drug use.

III. Evidence quality and future research planning of Leonurus injection

Motherwort injection is the dominant dosage form of motherwort Chinese patent medicine, there are only 4 systematic reviews in the literature, and all of them are studies on the prevention and treatment of postpartum hemorrhage with motherwort injection, and 133 clinical randomized controlled trials, but the quality of the literature is generally low. Combined with the trend of bibliometric curve and the present situation of clinical application, we believe that it is urgent to carry out full component analysis under careful top-level design for the dominant dosage forms of motherwort. It is necessary to carry out the production of high-quality clinical evidence (applicability, effectiveness, safety, economy and its comprehensive evaluation), basic research evidence, transformation evidence and economic evidence. At the same time, we should optimize the supplementary drug instructions, formulate clinical guidelines and clinical pathways. In addition, based on the high-quality research evidence, the dominant dosage forms and usage of motherwort for other new indications can be further developed.